Sildenafil citrate-d8

Catalog No.: A31741
Stable Isotope
Sildenafil citrate-d8 is a deuterium-labeled derivative of Sildenafil citrate, a potent inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 5.22 nM. This stable isotope reagent is primarily used for metabolic studies and pharmacokinetic research, facilitating the tracing of drug metabolism and pharmacological profiling in biological systems. Its unique labeling allows for enhanced detection and analysis in various experimental formats.
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5mg
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSildenafil citrate-d8 is a deuterium-labeled derivative of Sildenafil citrate, a potent inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 5.22 nM. This stable isotope reagent is primarily used for metabolic studies and pharmacokinetic research, facilitating the tracing of drug metabolism and pharmacological profiling in biological systems. Its unique labeling allows for enhanced detection and analysis in various experimental formats.
Product Information
Catalog NumA31741
FormulaC28H30D8N6O11S
Molecular Weight674.75
CAS Number1215071-03-6
SMILESOC(CC(C(O)=O)(O)CC(O)=O)=O.CCOC1=C(C(NC2=C3N(N=C2CCC)C)=NC3=O)C=C(C=C1)S(=O)(N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C)=O
SynonymsUK-92480 citrate-d8
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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