SphK1-IN-4

Catalog No.: A65523
SphK1 Inhibitor
SphK1-IN-4 is a selective inhibitor of sphingosine kinase 1 (SphK1), an enzyme involved in sphingolipid metabolism. This compound has demonstrated potent inhibitory effects on SphK1 activity, making it a valuable tool for investigating the role of sphingosine kinase in cancer biology, particularly in lung cancer research. Its application can facilitate the exploration of therapeutic strategies targeting SphK1 in various cancer models.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSphK1-IN-4 is a selective inhibitor of sphingosine kinase 1 (SphK1), an enzyme involved in sphingolipid metabolism. This compound has demonstrated potent inhibitory effects on SphK1 activity, making it a valuable tool for investigating the role of sphingosine kinase in cancer biology, particularly in lung cancer research. Its application can facilitate the exploration of therapeutic strategies targeting SphK1 in various cancer models.
Product Information
Catalog NumA65523
FormulaC16H9ClN2O2
Molecular Weight296.71
CAS Number160149-21-3
SMILESO=C1OC2=C(C=C(Cl)C=C2)C=C1C3=NC4=CC=CC=C4N3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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