Catalog No.: A10869

c-Met inhibitor


SU11274 Chemical Structure

CAS NO. 658084-23-2

SU11274 is a Met tyrosine kinase inhibitor.

Availability: In stock

Package Price Qty
5 mg
10 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

SU11274 is a Met tyrosine kinase inhibitor.
Target Value
MetIC50: 0.01μM
Flk1IC50: 1.25μM
RONIC50: 4.0μM
FGFR1IC50: 8.5μM
CDK2IC50: >10μM
PDGFRβIC50: >20μM
EGFRIC50: >100μM
In vitro (25°C) DMSO 83 mg/mL (146.1 mM)
Water Insoluble
Ethanol 2 mg/mL
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.6 mL 88.01 mL 176.03 mL
0.5 mM 3.52 mL 17.6 mL 35.21 mL
1 mM 1.76 mL 8.8 mL 17.6 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10869
Actions Inhibitor
CAS No. 658084-23-2
Formula C28H30CIN5O4S
M. Wt 568.1
Purity >98%
Synonyms SU-11274, PKI-SU11274
SMILES CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)/C=C\3/C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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