TGFβRI-IN-5 is a selective inhibitor of TGFβRI, exhibiting a potent inhibitory activity with an IC50 of 0.08 μM. This compound demonstrates significant anticancer efficacy, showing 5–7 times greater activity compared to reference agents across a range of tested cell lines. Furthermore, TGFβRI-IN-5 promotes apoptosis and effectively arrests the cell cycle at the G2/M phase, making it a valuable tool for investigating TGFβ signaling in cancer research and therapeutic applications.
TGFβRI-IN-5 is a selective inhibitor of TGFβRI, exhibiting a potent inhibitory activity with an IC50 of 0.08 μM. This compound demonstrates significant anticancer efficacy, showing 5–7 times greater activity compared to reference agents across a range of tested cell lines. Furthermore, TGFβRI-IN-5 promotes apoptosis and effectively arrests the cell cycle at the G2/M phase, making it a valuable tool for investigating TGFβ signaling in cancer research and therapeutic applications.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
