CZC24832

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PI3K inhibitor

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Catalog No. A11363

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CZC24832 5mg A11363-5

Regular Price: $80.00

Special Price: $64.00

CZC24832 10mg A11363-10

Regular Price: $140.00

Special Price: $112.00

CZC24832 25mg A11363-25

Regular Price: $280.00

Special Price: $224.00

CZC24832 50mg A11363-50

Regular Price: $480.00

Special Price: $384.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).

CZC24832

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Chemical Information

Catalog Num A11363
Actions Inhibitor
M. Wt 364.4
Formula C15H17FN6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1159824-67-5
Synonyms CZC 24832, CZC-24832
SMILES code CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
Chemical Name 5-(2-Amino-8-fluoro[1,2,4]triazolo[?1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridi?nesulfonamide

Biological Activity

Description
CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
Targets
PI3Kγ PI3Kβ PI3Kδ
27 nM1.1 μM8.2 μM

Solubility

Solubility (25°C) * In vitro DMSO 5 mg/mL heating (13.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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