LY 2874455
Catalog No.: A11244
FGFR/VEGFR2 inhibitor
LY2874455 is a novel and potent FGFR/VEGFR Inhibitor.
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Research use only. We do not sell to patients.
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Biological Activity
| Description | LY2874455 is a novel and potent FGFR/VEGFR Inhibitor. | ||
|---|---|---|---|
| Targets |
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Product Information
| Catalog Num | A11244 |
|---|---|
| Formula | C21H19Cl2N5O2 |
| Molecular Weight | 444.31 |
| CAS Number | 1254473-64-7 |
| SMILES | C[C@H](C1=C(C=NC=C1Cl)Cl)OC2=CC3=C(C=C2)NN=C3/C=C/C4=CN(N=C4)CCO |
| Synonyms | LY-2874455, LY2874455 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 86 mg/mL (193.55 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 56 mg/mL (126.03 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.51 mL | 112.53 mL | 225.07 mL |
| 0.5 mM | 4.5 mL | 22.51 mL | 45.01 mL |
| 1 mM | 2.25 mL | 11.25 mL | 22.51 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
