NSC-207895 (XI-006)

Catalog No.: A11179
MDMX Inhibitor

NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A549 cells (1 to 10 µM for 16 to 24 h) by suppressesing MDMX promoter transcription activity (IC50 = 2.5 µM in HT1080 cells), leading to enhanced p53 stabilization and activation.

Grouped product items
Product Name Price Stock Qty
NSC-207895 5mg
$90.00
In stock
NSC-207895 10mg
$160.00
In stock
NSC-207895 50mg
$700.00
In stock
NSC-207895 100mg
$1,200.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Biological Activity
Discription

NSC207895 is a cell-permeable benzofuroxan compound that downregulates the p53 negative regulator MDMX protein level in MCF-7, LNCaP, and A549 cells (1 to 10 µM for 16 to 24 h) by suppressesing MDMX promoter transcription activity (IC50 = 2.5 µM in HT1080 cells), leading to enhanced p53 stabilization and activation.

Targets
Target Value
Product Information
Catalog Num A11179
Formula C11H13N5O4
Molecular Weight 279.25
CAS Number 58131-57-0
SMILES CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
Synonyms NSC207895
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 0.39 mg/mL (1.39 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.81 mL 179.05 mL 358.1 mL
0.5 mM 7.16 mL 35.81 mL 71.62 mL
1 mM 3.58 mL 17.91 mL 35.81 mL
5 mM 0.72 mL 3.58 mL 7.16 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
Keywords: buy NSC-207895 (XI-006) | NSC-207895 (XI-006) Supplier | purchase NSC-207895 (XI-006) | NSC-207895 (XI-006) cost | NSC-207895 (XI-006) manufacturer | order NSC-207895 (XI-006) | NSC-207895 (XI-006) distributor | buy 58131-57-0 | 58131-57-0 Supplier | purchase 58131-57-0 | 58131-57-0 cost | 58131-57-0 manufacturer | order 58131-57-0 | 58131-57-0 distributor