SJ 172550

Catalog No.: A15352

MDMX inhibitor

SJ 172550

SJ 172550 Chemical Structure

CAS NO. 431979-47-4

SJ 172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.

Availability: In stock

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10 mg
$110.00
50 mg
$450.00
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Biological Activity

SJ 172550 is the first MDMX inhibitor with EC50 of 0.84 uM; binds reversibly to MDMX and effectively kills retinoblastoma cells in which the expression of MDMX is amplified.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.32 mL 116.59 mL 233.17 mL
0.5 mM 4.66 mL 23.32 mL 46.63 mL
1 mM 2.33 mL 11.66 mL 23.32 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 428.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15352
Actions Inhibitor
CAS No. 431979-47-4
Formula C22H21ClN2O5
M. Wt 428.87
Purity >98%
Synonyms SJ172550, SJ-172550
SMILES CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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