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Anidulafungin

Catalog No.: A13436

glucan synthase inhibitor

Anidulafungin

Anidulafungin Chemical Structure

CAS NO. 166663-25-8

Anidulafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1995 and commercially developed by Eli Lilly. Anidulafungin inhibits the synthesis of ??-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 400 citations.

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$90.00
50 mg
$140.00
10mM * 1mL in DMSO
$116.00
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Biological Activity

Anidulafungin is a semi-synthetic cyclic lipopeptide belonging to the echinocandin class that was reported in 1995 and commercially developed by Eli Lilly. Anidulafungin inhibits the synthesis of ??-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi and is extensively referenced in the literature with over 400 citations.
Targets
glucan synthase
In vitro DMSO Warmed: 88 mg/mL (77.18 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 8.77 mL 43.85 mL 87.7 mL
0.5 mM 1.75 mL 8.77 mL 17.54 mL
1 mM 0.88 mL 4.39 mL 8.77 mL
5 mM 0.18 mL 0.88 mL 1.75 mL

*The above data is based on the productmolecular weight 1140.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13436
Actions Inhibitor
CAS No. 166663-25-8
Formula C58H73N7O17
M. Wt 1140.25
Purity >98%
SMILES CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC=C(C=C7)O)O)O)[C@@H](C)O)C)O)O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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