Centaurein is a flavonoid that functions as an enhancer of the IFN-γ promoter, significantly up-regulating the activity of NFAT and NF-κB enhancers. It has been shown to increase IFN-γ expression in T and NK cells, resulting in elevated serum IFN-γ levels in murine models. Additionally, Centaurein induces complete relaxation of contractions in intact rat aortic rings and demonstrates protective effects against Listeria infection in mice, making it a valuable tool for research in immunology and vascular biology.
Centaurein is a flavonoid that functions as an enhancer of the IFN-γ promoter, significantly up-regulating the activity of NFAT and NF-κB enhancers. It has been shown to increase IFN-γ expression in T and NK cells, resulting in elevated serum IFN-γ levels in murine models. Additionally, Centaurein induces complete relaxation of contractions in intact rat aortic rings and demonstrates protective effects against Listeria infection in mice, making it a valuable tool for research in immunology and vascular biology.
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