Dot1L-IN-2

Name: Dot1L-IN-2
Brand: Adooq Bioscience
SKU: A20231
Rating: 5 (288 reviews)

Catalog No.: A20231

Dot1L inhibitor

Dot1L-IN-2 is a potent, selective and orally bioavailable inhibitor of Dot1L (a histone methyltransferase), with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively.

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Grouped product items
Size	Price	Stock
1mg	$315.00	In stock
5mg	$955.00	In stock
10mg	$1,595.00	In stock
25mg	$1,665.00	In stock
50mg	$2,175.00	In stock
100mg	$2,795.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

Dot1L-IN-2 is a potent, selective and orally bioavailable inhibitor of Dot1L (a histone methyltransferase), with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively.

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A20231
Formula	C27H24N8O
Molecular Weight	476.53
CAS Number	1940206-71-2
SMILES	CN1C=NC2=CC(OC3=CC=CC=C3N4C(C)=CC5=C4C=C(NC6=NC=CC(NC)=N6)C=C5)=CN=C21
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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