Catalog No.: A13257

Cysteine Protease inhibitor


E-64 Chemical Structure

CAS NO. 66701-25-5

E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.

Availability: In stock

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25 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

E-64 is an irreversible and selective cysteine protease inhibitor with IC50 of 9 nM for papain.
Cysteine protease
9 nM
In vitro DMSO Warmed: 61 mg/mL (170.67 mM)
Water Warmed: 9 mg/mL (25.18 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.98 mL 139.9 mL 279.79 mL
0.5 mM 5.6 mL 27.98 mL 55.96 mL
1 mM 2.8 mL 13.99 mL 27.98 mL
5 mM 0.56 mL 2.8 mL 5.6 mL

*The above data is based on the productmolecular weight 357.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13257
Actions Inhibitor
CAS No. 66701-25-5
Formula C15H27N5O5
M. Wt 357.41
Purity >98%
Synonyms E64, E 64
SMILES CC(C)C[[email protected]@H](C(=O)NCCCCN=C(N)N)NC(=O)[[email protected]@H]1[[email protected]](O1)C(=O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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