EP300/CBP-IN-2

Catalog No.: A40368
EP300/CBP Inhibitor
EP300/CBP-IN-2 is a potent inhibitor of the EP300 and CBP histone acetyltransferases, targeting the regulation of gene expression involved in cancer biology. This compound demonstrates significant biological activity in vivo, making it a valuable tool for investigating the role of these targets in tumorigenesis and potential therapeutic interventions. Its applications extend to cancer research, exploring novel strategies for epigenetic modulation in cancer treatment.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEP300/CBP-IN-2 is a potent inhibitor of the EP300 and CBP histone acetyltransferases, targeting the regulation of gene expression involved in cancer biology. This compound demonstrates significant biological activity in vivo, making it a valuable tool for investigating the role of these targets in tumorigenesis and potential therapeutic interventions. Its applications extend to cancer research, exploring novel strategies for epigenetic modulation in cancer treatment.
Product Information
Catalog NumA40368
FormulaC30H29D3F2N4O3
Molecular Weight537.62
CAS Number2379527-49-6
SMILESO=C1N(C2=CC(F)=C(C=C2)F)[C@@H](CCC1)C3=NC4=CC(C5=C(C)ON=C5C)=CC=C4N3[C@@H]6CC[C@H](CC6)OC([2H])([2H])[2H]
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