EPZ011989 trifluoroacetate is a selective inhibitor of the enzyme EZH2, exhibiting a Ki value of less than 3 nM. This compound is notable for its ability to effectively inhibit histone methylation, thereby demonstrating significant anti-tumor activity. EPZ011989 trifluoroacetate is applicable in cancer research, providing insights into the role of EZH2 in tumorigenesis. Additionally, it features an alkyne group that facilitates click chemistry applications, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compatible azide-containing molecules.
EPZ011989 trifluoroacetate is a selective inhibitor of the enzyme EZH2, exhibiting a Ki value of less than 3 nM. This compound is notable for its ability to effectively inhibit histone methylation, thereby demonstrating significant anti-tumor activity. EPZ011989 trifluoroacetate is applicable in cancer research, providing insights into the role of EZH2 in tumorigenesis. Additionally, it features an alkyne group that facilitates click chemistry applications, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with compatible azide-containing molecules.
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