EZH2-IN-2

Catalog No.: A26788
EZH2 Inhibitor
EZH2-IN-2 is a potent inhibitor of the EZH2 enzyme, exhibiting an IC50 of 64 nM and a TR-FRET IC50 of 20 nM. This compound facilitates research into the dysregulation of EZH2 activity, which is implicated in various cancer and precancerous conditions. EZH2-IN-2 serves as a valuable tool for studying the mechanisms of tumorigenesis and exploring therapeutic strategies targeting EZH2 pathways.
Grouped product items
Size Price Stock Qty
5mg
$205.00
In stock
10mg
$335.00
In stock
50mg
$820.00
In stock
100mg
$1,200.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEZH2-IN-2 is a potent inhibitor of the EZH2 enzyme, exhibiting an IC50 of 64 nM and a TR-FRET IC50 of 20 nM. This compound facilitates research into the dysregulation of EZH2 activity, which is implicated in various cancer and precancerous conditions. EZH2-IN-2 serves as a valuable tool for studying the mechanisms of tumorigenesis and exploring therapeutic strategies targeting EZH2 pathways.
Product Information
Catalog NumA26788
FormulaC36H46N6O3
Molecular Weight610.79
CAS Number2238821-31-1
SMILESO=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C3=CC=C(N4CCN(CC5CC5)CC4)N=C3C)=CC(N(C(C6CC6)=O)CC)=C2C
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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