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Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.76 mL | 108.82 mL | 217.63 mL |
| 0.5 mM | 4.35 mL | 21.76 mL | 43.53 mL |
| 1 mM | 2.18 mL | 10.88 mL | 21.76 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.35 mL |
*The above data is based on the productmolecular weight 459.488. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18328 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 459.488 |
| Formula | C21H17N9O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1642581-63-2 |
| Synonyms | SCC244, SCC 244 |
| SMILES | O=S(N1N=CC2=NC=C(C3=CN(C)N=C3)C=C21)(C4=CN=C5C=CC(C6=CN(C)N=C6)=CN54)=O |
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