Glumetinib (SCC-244)

Catalog No.: A18328

c-Met inhibitor

Glumetinib (SCC-244)

Glumetinib (SCC-244) Chemical Structure

CAS NO. 1642581-63-2

Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.

Availability: In stock

Package Price Qty
5 mg
$130.00
10 mg
$200.00
50 mg
$500.00
100 mg
$800.00
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Biological Activity

Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.
In vitro DMSO 10 mg/mL (21.76 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.76 mL 108.82 mL 217.63 mL
0.5 mM 4.35 mL 21.76 mL 43.53 mL
1 mM 2.18 mL 10.88 mL 21.76 mL
5 mM 0.44 mL 2.18 mL 4.35 mL

*The above data is based on the productmolecular weight 459.488. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18328
Actions Inhibitor
CAS No. 1642581-63-2
Formula C21H17N9O2S
M. Wt 459.488
Purity >98%
Synonyms SCC244, SCC 244
SMILES O=S(N1N=CC2=NC=C(C3=CN(C)N=C3)C=C21)(C4=CN=C5C=CC(C6=CN(C)N=C6)=CN54)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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