Glumetinib (SCC-244)

Name: Glumetinib (SCC-244)
Brand: Adooq Bioscience
SKU: A18328
Rating: 5 (288 reviews)

Catalog No.: A18328

c-Met inhibitor

Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.

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Glumetinib (SCC-244) 1642581-63-2 c-Met inhibitor

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Grouped product items
Size	Price	Stock
1mg	$45.00	In stock
5mg	$105.00	In stock
10mg	$165.00	In stock
25mg	$285.00	In stock
50mg	$430.00	In stock
100mg	$640.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	Glumetinib (SCC244) is a potent and highly selective c-Met kinase inhibitor with an IC50 of 0.42 nM. Glumetinib shows antitumor activity and a superior safety margin.

Product Information

Catalog Num	A18328
Formula	C21H17N9O2S
Molecular Weight	459.488
CAS Number	1642581-63-2
SMILES	O=S(N1N=CC2=NC=C(C3=CN(C)N=C3)C=C21)(C4=CN=C5C=CC(C6=CN(C)N=C6)=CN54)=O
Synonyms	SCC244, SCC 244
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	10 mg/mL (21.76 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.76 mL	108.82 mL	217.63 mL
0.5 mM	4.35 mL	21.76 mL	43.53 mL
1 mM	2.18 mL	10.88 mL	21.76 mL
5 mM	0.44 mL	2.18 mL	4.35 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂