LBH589 (Panobinostat)

Catalog No.: A10518

HDAC Inhibitor

LBH589 (Panobinostat)

LBH589 (Panobinostat) Chemical Structure

CAS NO. 404950-80-7

LBH589 is a hydroxamic acid and acts as a non-selective HDAC inhibitor with IC5o of HDAC1 to be 0.23 nM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $50.00

Special Price $40.00

50 mg

Regular Price: $110.00

Special Price $88.00

100 mg

Regular Price: $150.00

Special Price $120.00

200 mg

Regular Price: $250.00

Special Price $200.00

10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

LBH589 is a hydroxamic acid and acts as a non-selective HDAC inhibitor with IC5o of HDAC1 to be 0.23 nM.
Targets
HDAC (MOLT-4 cells) HDAC (Reh cells)
5 nM20 nM
In vitro (25°C) DMSO 69 mg/mL (197.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Add solvents to the product individually and in order: 2% DMSO+48% PEG 300+2% Tween 80+ddH2O 5
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.62 mL 143.1 mL 286.2 mL
0.5 mM 5.72 mL 28.62 mL 57.24 mL
1 mM 2.86 mL 14.31 mL 28.62 mL
5 mM 0.57 mL 2.86 mL 5.72 mL

*The above data is based on the productmolecular weight 349.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10518
Actions Inhibitor
M. Wt 349.4
Formula C21H23N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 404950-80-7
Synonyms NVP-LBH589, LBH-589
SMILES CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO

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