Total item
Cart Subtotal
$0.00 Biological Activity
Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.
Targets
| H-Ras-cRaf1 interaction | ||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.23 mL | 111.16 mL | 222.33 mL |
| 0.5 mM | 4.45 mL | 22.23 mL | 44.47 mL |
| 1 mM | 2.22 mL | 11.12 mL | 22.23 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.45 mL |
*The above data is based on the productmolecular weight 449.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13135 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 449.79 |
| Formula | C15H11ClF3N5O4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 436133-68-5 |
| Synonyms | Kobe-0065 |
| SMILES | CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
PD0325901
PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.
MEK162 (ARRY-438162, Binimetinib)
MEK162 (ARRY-438162) is a potent, selective, ATP uncompetitive inhibitor of MEK1/2.
GDC-0623
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
BIX 02189
BIX 02189 is a selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1…
RO4987655
RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineopl…
Chlortetracycline Hydrochloride
Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic.
BI-847325
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xen…
AS703026 (Pimasertib)
AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced oste…
Keywords:buy Kobe0065 | Kobe0065 Supplier | purchase Kobe0065 | Kobe0065 cost | Kobe0065 manufacturer | order Kobe0065 | Kobe0065 distributor | buy 436133-68-5| 436133-68-5 Supplier | purchase 436133-68-5 | 436133-68-5 cost | 436133-68-5 manufacturer | order 436133-68-5 | 436133-68-5 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.