Kobe0065

Catalog No.: A13135

Ras-Raf interaction inhibitor

Kobe0065

Kobe0065 Chemical Structure

CAS NO. 436133-68-5

Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $50.00

Special Price $40.00

25 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $135.00

Special Price $108.00

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.
Targets
H-Ras-cRaf1 interaction
In vitro DMSO 85 mg/mL (188.98 mM)
Water Insoluble
Ethanol 12 mg/mL (26.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.23 mL 111.16 mL 222.33 mL
0.5 mM 4.45 mL 22.23 mL 44.47 mL
1 mM 2.22 mL 11.12 mL 22.23 mL
5 mM 0.44 mL 2.22 mL 4.45 mL

*The above data is based on the productmolecular weight 449.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13135
Actions Inhibitor
CAS No. 436133-68-5
Formula C15H11ClF3N5O4S
M. Wt 449.79
Purity >98%
Synonyms Kobe-0065
SMILES CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy Kobe0065 | Kobe0065 Supplier | purchase | cost | manufacturer | order | distributor | buy 436133-68-5| 436133-68-5 Supplier | purchase 436133-68-5 | 436133-68-5 cost | 436133-68-5 manufacturer | order 436133-68-5 | 436133-68-5 distributor
Rewards