Kobe0065

Catalog No.: A13135

Ras-Raf interaction inhibitor

Kobe0065

Kobe0065 Chemical Structure

CAS NO. 436133-68-5

Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $50.00

Special Price $40.00

25 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $135.00

Special Price $108.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells.
Targets
H-Ras-cRaf1 interaction
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.23 mL 111.16 mL 222.33 mL
0.5 mM 4.45 mL 22.23 mL 44.47 mL
1 mM 2.22 mL 11.12 mL 22.23 mL
5 mM 0.44 mL 2.22 mL 4.45 mL

*The above data is based on the productmolecular weight 449.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A13135
Actions Inhibitor
M. Wt 449.79
Formula C15H11ClF3N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 436133-68-5
Synonyms Kobe-0065
SMILES CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl

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