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Other Lipids lists lipid-related compounds that fall outside the five main lipid classes of this section. Phenolic lipids are represented by 5-heptadecylresorcinol, an alkylresorcinol with a long saturated side chain that occurs in cereal bran. Linoleic acid derivatives include cis-coronaric acid, an epoxy fatty acid, and octadeca-9,12-dienamide, a primary fatty acid amide. 11-cis-Vaccenyl acetate is a fatty acyl ester that acts as a male pheromone in the fruit fly Drosophila melanogaster. ONO-4007 is a synthetic analog of lipid A, the glycolipid anchor of bacterial lipopolysaccharide. Riboflavin tetrabutyrate, a lipophilic ester of riboflavin (vitamin B2), is listed as well. Some entries are not lipids, such as plozasiran, a small interfering RNA (siRNA) directed at apolipoprotein C-III (APOC3).
Leucomentin-5 is a potent free radical scavenger that effectively inhibits lipid peroxidation, with an IC50 value of 0.11 μg/mL. This compound is utilized in research to explore oxidative stress and related cellular damage, making it a valuable tool in studies of various biological processes and pathologies.
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Synonyms: (2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaen-1-ol
Undecaprenol is a long-chain isoprenoid alcohol that serves as a key lipid precursor in bacterial cell walls. It plays a crucial role in the biosynthesis of peptidoglycan, which is essential for maintaining bacterial integrity and architecture. This compound is utilized in research applications focused on bacterial biology, antibiotic development, and synthetic biology. Its function in lipid metabolism makes it a valuable reagent for exploring cellular processes and developing novel antimicrobial strategies.
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E12CA1A3 is a lipid transfection reagent designed to enhance the delivery efficiency of mRNA into cells. This reagent facilitates the effective transport of nucleotides across cellular membranes, promoting successful transfection and subsequent gene expression. It is particularly useful in research applications involving gene therapy, vaccine development, and functional studies of gene regulation.
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ML261 is a potent inhibitor of hepatic lipid droplet formation, exhibiting an IC50 value of 69.7 nM. This compound is valuable for research into non-alcoholic fatty liver disease (NAFLD) and related inflammatory processes, allowing for exploration of therapeutic strategies targeting lipid metabolism and hepatic function.
Derpanicate is a nicotinic acid ester that primarily functions as a lipid-modifying agent. It exhibits antihypercholesterolemic properties, contributing to the reduction of cholesterol levels in the bloodstream. Additionally, Derpanicate demonstrates vasodilatory effects, potentially aiding in the improvement of blood flow. This compound is applicable in pharmacological research focusing on cardiovascular health and cholesterol management.
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Thio-Miltefosine is a membrane phase regulator that modulates lipid raft behavior in cellular membranes. By influencing the phase dynamics of membrane structures, it affects cellular processes and signaling pathways. This compound is valuable for research applications studying membrane biophysics, lipid metabolism, and the role of lipid rafts in various biological functions.
Synonyms: Sgd 24774
Beclobrate is a fibric acid derivative that functions as a lipid-lowering agent. It demonstrates significant efficacy in reducing lipid levels, as evidenced by studies conducted in rodent models. Beclobrate is primarily utilized in research exploring lipid metabolism and interventions for dyslipidemia.
Synonyms: Piperazine sultosylate; A-585
Sultosilic acid piperazine salt is a lipid-lowering agent that modifies blood lipid levels and reduces platelet adhesiveness. It operates without promoting peroxisomal activity in hepatocytes, minimizing the risk of adverse side effects. This compound is relevant for research applications focused on dyslipidemia and cardiovascular health.
LP238-p is a lipid molecule that functions primarily as a modulator of cell membrane dynamics. Its unique properties enable it to influence cell signaling and membrane fluidity, making it a valuable tool in studies of cellular processes. LP238-p is useful in research applications focusing on lipid metabolism, cellular signaling pathways, and membrane-related phenomena.
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SDZ-MRL 953 is a novel immunostimulatory lipid analogue that operates by enhancing immune responses without inducing pulmonary toxicity. Its safety profile supports its potential use in research focused on acute lung injury, making it a valuable tool for investigations into inflammatory responses and therapeutic strategies in pulmonary conditions.
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Phenochalasin A is a lipid droplets inhibitor that effectively reduces both the number and size of lipid droplets in macrophages at concentrations below 20 μM. This compound demonstrates a lack of cytotoxicity, making it a valuable tool for studying lipid metabolism and the role of lipid droplets in cellular processes. Phenochalasin A is applicable in research focused on metabolic disorders and related therapeutic developments.
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Cholyl-cadaverine is a polyamine bile amidate that primarily interacts with lipid membranes. This compound is of interest in studying lipid metabolism and membrane biophysics. Its unique structure allows for investigation into its biological activities, making it a valuable tool in research focused on lipid-related pathways and their implications in various disease states.
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Phenazostatin B is a phenazine compound that functions as a neuroprotectant by scavenging free radicals and inhibiting lipid peroxidation. It demonstrates protective effects on N18-RE-105 nerve cells, mitigating glutamate-induced toxicity with an EC50 value of 0.33 μg/mL. This compound is relevant for research focused on neuroprotection and cell survival in neurodegenerative studies.
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Azo SM is a photoswitchable lipid that enables controlled manipulation of lipid bilayers upon exposure to light. Its unique ability to transition between different conformations allows for studies in membrane dynamics and cellular interactions. Azo SM is particularly useful in research applications involving photophysics and the development of novel biosensors.
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18:1 Dimethylacetal is an ether lipid that serves as a structural component in cellular membranes. Known for its role in maintaining membrane integrity and fluidity, it is utilized in studies focused on lipid metabolism, cellular signaling, and membrane-associated phenomena. This compound is instrumental in exploring the effects of lipid composition on cellular functions.
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Synonyms: N-palMitoyl L-serine Methyl ester
N-16:0 L-Serine MeEster is an amino acid amphiphile that targets lipid interactions. This compound serves as an important tool in membrane biology research and lipid-related studies due to its ability to modulate lipid bilayer properties. Its unique structure enables applications in drug delivery systems and the exploration of membrane dynamics.
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7.7 MAG is a lipid-based detergent that facilitates protein crystallization. It promotes the solubilization of membrane proteins, enhancing their stability and allowing for improved structure determination. This reagent is essential for researchers studying membrane protein interactions and structural biology applications.
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18:0 Dimethylacetal is a type of ether lipid that serves as a critical component of cellular membranes. This compound plays a significant role in membrane structure and function, making it valuable for studies related to lipid metabolism and membrane biophysics. Its unique properties enable researchers to investigate the dynamics of lipid bilayers and their implications in various biological processes.
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Synonyms: Δ9-Tetrahydrocannabiphorolic acid; (-)-trans-Δ9-THCPA
Δ9-THCPA-A is a phytocannabinoid that primarily interacts with lipid pathways. Known for its ability to modulate endocannabinoid signaling, this compound has potential applications in studying the physiological roles of cannabinoids in various biological systems. Researchers may utilize Δ9-THCPA-A to explore its effects on lipid metabolism, neuroprotection, and inflammatory responses.
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17:0 Cyclo acid is a cyclopropyl lipid that serves as a structural component in various lipid-based studies. It is utilized in research focused on lipid metabolism, membrane dynamics, and the development of lipid-based therapeutics. Its unique structure provides valuable insights into lipid interactions and functionalities in biological systems.
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