LLC0424

Name: LLC0424
Brand: Adooq Bioscience
SKU: A23964
Rating: 5 (288 reviews)

Catalog No.: A23964

PROTAC NSD2 Degrader

LLC0424 is a potent and selective cereblon-based PROTAC that targets NSD2 for degradation. It induces NSD2 degradation in a cereblon- and proteasome-dependent manner, with a DC₅₀ of 20 nM in RPMI-8402 cells.

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LLC0424 3061315-33-8 PROTAC NSD2 Degrader

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Grouped product items
Size	Price	Stock
1mg	$360.00	In stock
5mg	$960.00	In stock
10mg	$1,620.00	In stock
50mg	$4,520.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	LLC0424 is a potent and selective cereblon-based PROTAC that targets NSD2 for degradation. It induces NSD2 degradation in a cereblon- and proteasome-dependent manner, with a DC₅₀ of 20 nM in RPMI-8402 cells.

Product Information

Catalog Num	A23964
Formula	C45H41N7O9
Molecular Weight	823.85
CAS Number	3061315-33-8
SMILES	O=C(N1)COC2=C1C=CC(C(N(C3CC3)CC4=CC=C(C(NC5=CC=C(C(NC6CCN(C7=CC8=C(C(N(C(C(N9)=O)CCC9=O)C8=O)=O)C=C7)CC6)=O)C=C5)=O)C=C4)=O)=C2
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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