Obeticholic Acid

Catalog No.: A13866

FXR agonist

Obeticholic Acid

Obeticholic Acid Chemical Structure

CAS NO. 459789-99-2

Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM

Availability: In stock

Package Price Qty
10 mg

Regular Price: $70.00

Special Price $63.00

50 mg

Regular Price: $240.00

Special Price $216.00

10mM * 1mL in DMSO

Regular Price: $55.00

Special Price $49.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM
Targets
FXR
99 nM(EC50)
In vitro DMSO 84 mg/mL (199.7 mM)
Water <1 mg/mL (<1 mM)
Ethanol 84 mg/mL (199.7 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.77 mL 118.87 mL 237.74 mL
0.5 mM 4.75 mL 23.77 mL 47.55 mL
1 mM 2.38 mL 11.89 mL 23.77 mL
5 mM 0.48 mL 2.38 mL 4.75 mL

*The above data is based on the productmolecular weight 420.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13866
Actions Agonist
M. Wt 420.63
Formula C26H44O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 459789-99-2
Synonyms INT-747, 6-ECDCA
SMILES CC[[email protected]@H]1[[email protected]@H]2C[[email protected]@H](CC[[email protected]@]2([[email protected]]3CC[[email protected]]4([[email protected]]([[email protected]@H]3[[email protected]@H]1O)CC[[email protected]@H]4[[email protected]](C)CCC(=O)O)C)C)O

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