Biochemical Assay Reagents

Cat. No.

A65631

CAS No.

2586047-09-6

CDN-A

CDN-A is a cyclic di-nucleotide that serves as a potent stimulator of both innate and adaptive immune responses. It facilitates the synthesis of antibody-drug conjugates (ADCs) and plays a crucial role in immune regulation by activating interferon gene expression. In humans, cyclic di-nucleotides are produced endogenously in response to foreign DNA or by bacterial pathogens, making them vital for stimulating the innate immune system. Research applications include immunotherapy and the study of immune response mechanisms.

Cat. No.

A86471

CAS No.

14379-00-1

Croconic acid disodium

Synonyms: Nacr

Croconic acid disodium is a potent activator of lysine crotonylation (Kcr), promoting cell growth and proliferation through the upregulation of genes associated with Kcr modification. This compound is particularly relevant for enhancing the efficiency of somatic cell nuclear transfer (SCNT) and optimizing conditions in cell culture studies, making it a valuable reagent for researchers focused on cellular dynamics and development.

Cat. No.

A89020

CAS No.

30403-47-5

1,2-Dihexanoyl-sn-glycerol

1,2-Dihexanoyl-sn-glycerol is a potent activator of protein kinase C (PKC), functioning through the generation of diacylglycerol (DAG) as a second messenger. This compound is utilized as a biochemical assay reagent to study PKC signaling pathways and their effects on various cellular processes. While its biological activity is not fully characterized, it is anticipated to exhibit similar properties to 1,2-dioctanoyl-sn-glycerol, supporting its application in research involving lipid signaling and cell regulation.

Cat. No.

A93170

CAS No.

1212331-85-5

8(R)-Hydroxyoctadecanoic acid

8(R)-Hydroxyoctadecanoic acid is an ester product known for its role in lipid metabolism. This compound exhibits biological activity as an activator of peroxisome proliferator-activated receptors (PPARs), which are involved in the regulation of fatty acid storage and glucose metabolism. It can be utilized in research applications focused on metabolic disorders, inflammation, and cardiovascular diseases, providing insights into the physiological roles of fatty acids in cellular processes.

Cat. No.

A93290

CAS No.

911102-04-0

BocNH-PEG2-CH2COONHS

BocNH-PEG2-CH2COONHS is a PEG-derived biochemical assay reagent that features a terminal carboxylic acid and a Boc-protected amino group. This hydrophilic PEG spacer enhances the solubility of compounds in aqueous solutions, facilitating diverse biochemical applications. The terminal carboxylic acid readily reacts with primary amine groups, particularly in conjunction with activators like EDC and HATU, to yield stable amide bonds. Deprotection of the Boc group under mild acidic conditions generates a free amine for subsequent reactions.

Cat. No.

A93446

CAS No.

179763-60-1

3-((2-(4-Azidobenzamido)ethyl)disulfanyl)propanoic acid

3-((2-(4-Azidobenzamido)ethyl)disulfanyl)propanoic acid is a versatile biochemical assay reagent featuring an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide can be activated with UV light (250 to 350 nm) facilitating biomolecule conjugation. Additionally, the carboxylic acid allows for amide bond formation with amines in the presence of an activator, while the disulfide bond can be cleaved using reducing agents, making this compound useful for various chemical biology applications and protein labeling studies.

Cat. No.

A93858

CAS No.

191163-45-8

4-Azide-TFP-amide-SS-propionic acid

4-Azide-TFP-amide-SS-propionic acid is a biochemical assay reagent featuring an aryl azide, a cleavable disulfide bond, and a carboxylic acid. The aryl azide undergoes photo-activation with UV light (250 to 350 nm), facilitating conjugation with various biomolecules. The carboxylic acid is reactive towards amines in the presence of an activator, allowing for the formation of stable amide bonds. The associated disulfide bond can be selectively cleaved using reducing agents, making this compound valuable for applications in protein labeling and conjugation studies.

Cat. No.

A94952

CAS No.

2566404-74-6

4-Azide-TFP-amide-PEG4-acid

4-Azide-TFP-amide-PEG4-acid is a biochemical assay reagent designed for efficient conjugation reactions. Featuring an aryl azide that can be photo-activated under UV light (250 to 350 nm), it facilitates the covalent attachment to various biomolecules. The inclusion of a PEG spacer enhances aqueous solubility and minimizes steric hindrance during ligation, while the carboxylic acid moiety allows for amine reactions in the presence of an activator to generate stable amide bonds. This reagent is suitable for applications in bioconjugation chemistry and the development of novel biosensors.