Pantinin-1

Catalog No.: A32453
Antimicrobial Peptide
Pantinin-1 is an antimicrobial peptide derived from the venom of the Pandinus imperator scorpion, primarily targeting microbial pathogens. It exhibits potent antimicrobial activity against Gram-positive bacteria and fungi, while displaying minimal efficacy against Gram-negative bacteria; it also shows low hemolytic activity towards human erythrocytes. Additionally, Pantinin-1 demonstrates anticancer properties by inducing apoptosis in tumor cells, making it a valuable reagent for research in antimicrobial and cancer therapies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPantinin-1 is an antimicrobial peptide derived from the venom of the Pandinus imperator scorpion, primarily targeting microbial pathogens. It exhibits potent antimicrobial activity against Gram-positive bacteria and fungi, while displaying minimal efficacy against Gram-negative bacteria; it also shows low hemolytic activity towards human erythrocytes. Additionally, Pantinin-1 demonstrates anticancer properties by inducing apoptosis in tumor cells, making it a valuable reagent for research in antimicrobial and cancer therapies.
Product Information
Catalog NumA32453
FormulaC75H119N17O18
Molecular Weight1546.85
CAS Number2383114-96-1
SequenceGly-Ile-Leu-Gly-Lys-Leu-Trp-Glu-Gly-Phe-Lys-Ser-Ile-Val
Sequence shorteningGILGKLWEGFKSIV
SMILESC([C@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC(CN)=O)[C@H](CC)C)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)C(N[C@H](C(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@@H](C)C)C(O)=O)=O)[C@H](CC)C)=O)CO)=O)CCCCN)=O)=O)=O)CCC(O)=O)=O)C=2C=3C(NC2)=CC=CC3
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