PYR-41
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Important Notice: For research use only. We do not sell to patients.
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Discription | PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM). | ||
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Targets |
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Catalog Num | A13254 |
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Formula | C17H13N3O7 |
Molecular Weight | 371.3 |
CAS Number | 418805-02-4 |
SMILES | CCOC(=O)C1=CC=C(C=C1)N2C(=O)/C(=C\C3=CC=C(O3)[N+](=O)[O-])/C(=O)N2 |
Synonyms | PYR 41, PYR41 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 72 mg/mL (193.9 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.93 mL | 134.66 mL | 269.32 mL |
0.5 mM | 5.39 mL | 26.93 mL | 53.86 mL |
1 mM | 2.69 mL | 13.47 mL | 26.93 mL |
5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2