PYR-41

Catalog No.: A13254

Ubiquitin E1 Inhibitor

PYR-41 Chemical Structure

CAS NO. 418805-02-4

PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM).

Availability: Out of stock

Package Price
10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $300.00

Special Price $240.00

100 mg

Regular Price: $500.00

Special Price $400.00

10mM * 1mL in DMSO
$65.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PYR-41 is a cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor (IC50 < 10 μM).
Targets
Ubiquitin-activating Enzyme E1 (Cell-free assay)
<10 μM
In vitro DMSO 74 mg/mL (199.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.93 mL 134.66 mL 269.32 mL
0.5 mM 5.39 mL 26.93 mL 53.86 mL
1 mM 2.69 mL 13.47 mL 26.93 mL
5 mM 0.54 mL 2.69 mL 5.39 mL

*The above data is based on the productmolecular weight 371.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13254
Actions Inhibitor
M. Wt 371.3
Formula C17H13N3O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 418805-02-4
Synonyms PYR 41, PYR41
SMILES CCOC(=O)C1=CC=C(C=C1)N2C(=O)/C(=C\C3=CC=C(O3)[N+](=O)[O-])/C(=O)N2

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