Catalog No.: A13839

bradykinin B1 receptor antagonist


SSR240612 Chemical Structure

CAS NO. 464930-42-5

SSR240612 is a new antagonist of the bradykinin B1 receptor.

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  • Ling Qin, .et al. Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis, Arthritis Res Ther, 2019, 21:12 PMID: 30621761

Biological Activity

SSR240612 is a new antagonist of the bradykinin B1 receptor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.6 mL 63.02 mL 126.04 mL
0.5 mM 2.52 mL 12.6 mL 25.21 mL
1 mM 1.26 mL 6.3 mL 12.6 mL
5 mM 0.25 mL 1.26 mL 2.52 mL

*The above data is based on the productmolecular weight 793.411. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13839
Actions Antagonist
CAS No. 464930-42-5
Formula C42H53ClN4O7S
M. Wt 793.411
Purity >98%
Synonyms SSR 240612, SSR-240612
SMILES C[[email protected]@H]1CCC[[email protected]@H](N1CC2=CC=C(C=C2)C[[email protected]](C(=O)N(C)C(C)C)NC(=O)C[[email protected]](C3=CC4=C(C=C3)OCO4)NS(=O)(=O)C5=CC6=C(C=C5)C=C(C=C6)OC)C.Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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