Tyrphostin AG 879

Catalog No.: A10053

HER2 inhibitor

Tyrphostin AG 879 Chemical Structure

CAS NO. 148741-30-4

Tyrphostin AG 879 is an inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA.

Availability: In stock

Package Price Qty
5 mg
$25.00
10 mg
$40.00
25 mg
$80.00
50 mg
$140.00
10mM * 1mL in DMSO
$75.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Tyrphostin AG 879 is an inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA.
Targets
HER2-Neu Trk PDGFR EGFR
1.0 μM10 μM>100 μM>500 μM
In vitro (25°C) DMSO 36 mg/mL (113.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (9.47 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.6 mL 157.98 mL 315.96 mL
0.5 mM 6.32 mL 31.6 mL 63.19 mL
1 mM 3.16 mL 15.8 mL 31.6 mL
5 mM 0.63 mL 3.16 mL 6.32 mL

*The above data is based on the productmolecular weight 316.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10053
Actions Inhibitor
M. Wt 316.5
Formula C18H24N2OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 148741-30-4
Synonyms AG879
SMILES CC(C)(C)C1=CC(=C/C(=C(/N)\S)/C#N)C=C(C1=O)C(C)(C)C

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