Tyrphostin AG 879

Catalog No.: A10053

HER2 inhibitor

Tyrphostin AG 879

Tyrphostin AG 879 Chemical Structure

CAS NO. 148741-30-4

Tyrphostin AG 879 is an inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA.

Availability: In stock

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5 mg

Regular Price: $25.00

Special Price $20.00

10 mg

Regular Price: $40.00

Special Price $32.00

25 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $140.00

Special Price $112.00

10mM * 1mL in DMSO

Regular Price: $75.00

Special Price $60.00

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Biological Activity

Tyrphostin AG 879 is an inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA.
Targets
HER2-Neu Trk PDGFR EGFR
1.0 μM10 μM>100 μM>500 μM
In vitro (25°C) DMSO 35 mg/mL (110.59 mM)
Water Insoluble
Ethanol 3 mg/mL (9.47 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.6 mL 157.98 mL 315.96 mL
0.5 mM 6.32 mL 31.6 mL 63.19 mL
1 mM 3.16 mL 15.8 mL 31.6 mL
5 mM 0.63 mL 3.16 mL 6.32 mL

*The above data is based on the productmolecular weight 316.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10053
Actions Inhibitor
CAS No. 148741-30-4
Formula C18H24N2OS
M. Wt 316.5
Solubility DMSO
Purity >98%
Synonyms AG879
SMILES CC(C)(C)C1=CC(=C/C(=C(/N)\S)/C#N)C=C(C1=O)C(C)(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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