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NVP-BKM120 Hydrochloride

PI3K Inhibitor‎

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Catalog No. A15195

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NVP-BKM120 Hydrochloride 5mg A15195-5

Regular Price: $60.00

Special Price: $48.00

NVP-BKM120 Hydrochloride 10mg A15195-10

Regular Price: $90.00

Special Price: $72.00

NVP-BKM120 Hydrochloride 50mg A15195-50

Regular Price: $150.00

Special Price: $120.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110??/??/??/?? with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4K??.

NVP-BKM120 Hydrochloride

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Chemical Information

Catalog Num A15195
Actions Inhibitor
M. Wt 446.85
Formula C18H21F3N6O2.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1312445-63-8
Synonyms BKM-120 hydrochloride, BKM120 hydrochloride, BKM 120 hydrochloride
SMILES code C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4.Cl
Chemical Name 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine hydrochloride (1:1)

Biological Activity

Description
NVP-BKM120 Hydrochloride is a selective PI3K inhibitor of p110??/??/??/?? with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4K??.

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