PIK-90

Catalog No.: A10730

PI3K Inhibitor

PIK-90

PIK-90 Chemical Structure

CAS NO. 677338-12-4

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$60.00
50 mg
$160.00
100 mg
$280.00
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Biological Activity

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.
Targets
PI3Kα PI3Kγ PI3Kδ PI3Kβ
11 nM18 nM58 nM350 nM
In vitro (25°C) DMSO 0.27 mg/mL (0.76 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80, pH 4 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.46 mL 142.29 mL 284.58 mL
0.5 mM 5.69 mL 28.46 mL 56.92 mL
1 mM 2.85 mL 14.23 mL 28.46 mL
5 mM 0.57 mL 2.85 mL 5.69 mL

*The above data is based on the productmolecular weight 351.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10730
Actions Inhibitor
CAS No. 677338-12-4
Formula C18H17N5O3
M. Wt 351.4
Purity >98%
Synonyms PIK90
SMILES COC1=C(C2=C(C=C1)C3=NCCN3C(=N2)NC(=O)C4=CN=CC=C4)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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