Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
Biological Activity
PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 α, β, γ and δ isoforms, low mTOR activity.
Targets
PI3Kα | PI3Kγ | PI3Kδ | PI3Kβ | |
11 nM | 18 nM | 58 nM | 350 nM |
In vitro (25°C) | DMSO | 0.27 mg/mL (0.76 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80, pH 4 | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.46 mL | 142.29 mL | 284.58 mL |
0.5 mM | 5.69 mL | 28.46 mL | 56.92 mL |
1 mM | 2.85 mL | 14.23 mL | 28.46 mL |
5 mM | 0.57 mL | 2.85 mL | 5.69 mL |
*The above data is based on the productmolecular weight 351.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10730 |
---|---|
Actions | Inhibitor |
CAS No. | 677338-12-4 |
Formula | C18H17N5O3 |
M. Wt | 351.4 |
Purity | >98% |
Synonyms | PIK90 |
SMILES | COC1=C(C2=C(C=C1)C3=NCCN3C(=N2)NC(=O)C4=CN=CC=C4)OC |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy PIK-90 | PIK-90 Supplier | purchase | cost | manufacturer | order | distributor | buy 677338-12-4| 677338-12-4 Supplier | purchase 677338-12-4 | 677338-12-4 cost | 677338-12-4 manufacturer | order 677338-12-4 | 677338-12-4 distributor