SB590885

Catalog No.: A10829
B-Raf Inhibitor
SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively.
Grouped product items
Product Name Price Stock Qty
SB590885 5mg
$90.00
In stock
SB590885 10mg
$136.00
In stock
SB590885 50mg
$450.00
In stock
SB590885 100mg
$750.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively.
Targets
Target Value
Product Information
Catalog Num A10829
Formula C27H27N5O2
Molecular Weight 453.5
CAS Number 405554-55-4
SMILES CN(C)CCOC1=CC=C(C=C1)C2=N/C(=C\3/C=CC4=C(CCC4=C3)N=O)/C(=C5C=CNC=C5)N2
Synonyms SB-590885
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 5 mg/mL (11.02 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% Cremophor EL, 2% N,N-dimethylacetamide, pH 5.0 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.25 mL 220.51 mL
0.5 mM 4.41 mL 22.05 mL 44.1 mL
1 mM 2.21 mL 11.03 mL 22.05 mL
5 mM 0.44 mL 2.21 mL 4.41 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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