SU-5402

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VEGFR/FGFR inhibitor‎

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Catalog No. A11558

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SU-5402 5mg A11558-5

Regular Price: $60.00

Special Price: $51.00

SU-5402 10mg A11558-10

Regular Price: $100.00

Special Price: $85.00

SU-5402 25mg A11558-25

Regular Price: $200.00

Special Price: $170.00

SU-5402 50mg A11558-50

Regular Price: $350.00

Special Price: $297.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).

SU-5402

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Chemical Information

Catalog Num A11558
Actions Inhibitor
M. Wt 296.32
Formula C17H16N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 215543-92-3
Synonyms SU5402, SU 5402
SMILES code CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O
Chemical Name 2-[(1,2-Dihydro-2-oxo-3H-indol-3-yl?idene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid

Biological Activity

Description
SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).
Targets
VEGFR2 FGFR1 PDGFRβ
20 nM30 nM510 nM

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