Wnt-C59

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PORCN/Wnt inhibitor

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Catalog No. A12951

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Wnt-C59 5mg A12951-5

Regular Price: $80.00

Special Price: $68.00

Wnt-C59 10mg A12951-10

Regular Price: $130.00

Special Price: $110.50

Wnt-C59 25mg A12951-25

Regular Price: $260.00

Special Price: $221.00

Wnt-C59 50mg A12951-50

Regular Price: $500.00

Special Price: $425.00

Wnt-C59 10mM * 1mL in DMSO A12951-10mM-D

Regular Price: $127.00

Special Price: $107.95

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.

Wnt-C59

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Chemical Information

Catalog Num A12951
Actions Inhibitor
M. Wt 379.45
Formula C25H21N3O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1243243-89-1
Synonyms WntC59
SMILES code CC1=NC=CC(=C1)C2=CC=C(C=C2)CC(=O)NC3=CC=C(C=C3)C4=CN=CC=C4
Chemical Name 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide

Biological Activity

Description
Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
Targets
Porcn (HEK293 cells )
74 pM

Solubility

Solubility (25°C) * In vitro DMSO 76 mg/mL (200.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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