IWP-L6

Catalog No.: A13978

PORCN inhibitor

IWP-L6 Chemical Structure

CAS NO. 1427782-89-5

IWP-L6 is a potent inhibitor of Porcupine (Porcn), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM).

Availability: In stock

Package Price Qty
10 mg
$85.00
25 mg
$180.00
50 mg
$300.00
10mM * 1mL in DMSO
$99.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

IWP-L6 is a potent inhibitor of Porcupine (Porcn), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM).
Targets
Porcn
0.5 nM(EC50)
In vitro DMSO 25 mg/mL heating (52.9 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.16 mL 105.8 mL 211.6 mL
0.5 mM 4.23 mL 21.16 mL 42.32 mL
1 mM 2.12 mL 10.58 mL 21.16 mL
5 mM 0.42 mL 2.12 mL 4.23 mL

*The above data is based on the productmolecular weight 472.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13978
Actions Inhibitor
M. Wt 472.58
Formula C25H20N4O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1427782-89-5
Synonyms IWP L6, IWPL6
SMILES C1CSC2=C1N=C(N(C2=O)C3=CC=CC=C3)SCC(=O)NC4=NC=C(C=C4)C5=CC=CC=C5

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