Dopamine Receptors

Dopamine receptor agonists and antagonists act on the five G protein-coupled receptors that respond to dopamine. The receptors form two groups, with D1 and D5 in the D1-like class and D2, D3 and D4 in the D2-like class. D1-like receptors stimulate adenylyl cyclase, whereas D2-like receptors inhibit it and lower cyclic adenosine monophosphate (cAMP) levels. Dopamine signaling controls movement, reward, motivation and hormone release, and is studied in Parkinson's disease and psychiatric research. Ligands here include the agonist rotigotine HCl, the D2 antagonists L-741626 and domperidone, and the D3-preferring ligand BP897.

2 Items

  • Rhamnose
    Cat. No.
    A35790

    Rhamnose

    Synonyms: L-Rhamnose

    Rhamnose (L-Rhamnose) is a naturally occurring deoxysugar that primarily targets inflammatory pathways. It has been shown to inhibit pro-inflammatory interleukins and matrix metalloproteinases (MMPs) in models of skin aging, highlighting its potential in anti-aging research. Additionally, Rhamnose enhances the phosphorylation of protein kinase A (PKA) substrates and hormone-sensitive lipase (HSL) in adipocytes, promoting PKA signaling and fat metabolism. Its ability to stimulate dopamine receptors and induce thermogenesis makes Rhamnose a valuable compound in obesity studies, while Rhamnose monohydrate is also utilized in research involving Ehrlich’s solid tumors and sarcomas.

    50 mg
    $25.00
    100 mg
    $30.00
    All 3 sizes
  • Prothipendyl hydrochloride
    Cat. No.
    B18274

    Prothipendyl hydrochloride

    Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent that primarily targets neurotransmitter pathways within the central nervous system. It exhibits sedative and psychomotor dampening effects, making it valuable for studying conditions related to psychomotor agitation, sleep disorders, and anxiety. Additionally, Prothipendyl hydrochloride serves as a substrate for various cytochrome P450 isozymes, including CYP1A2, CYP2D6, CYP2C19, and CYP3A4, providing insights into metabolic pathways involved in drug action and interaction.

    5 mg
    $290.00
    All 1 sizes

2 Items

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