AS703026 (Pimasertib)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation. | ||
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Targets |
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Catalog Num | A10089 |
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Formula | C15H15FIN3O3 |
Molecular Weight | 431.2 |
CAS Number | 1236699-92-5 |
SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O |
Synonyms | MSC1936369B |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 78 mg/mL (180.89 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 0.5% CMC+0.25% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.19 mL | 115.96 mL | 231.91 mL |
0.5 mM | 4.64 mL | 23.19 mL | 46.38 mL |
1 mM | 2.32 mL | 11.6 mL | 23.19 mL |
5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2