AS703026 (Pimasertib)

Name: AS703026 (Pimasertib)
Brand: Adooq Bioscience
SKU: A10089
Rating: 100 (268 reviews)

Catalog No.: A10089

MEK1/2 inhibitor

AS703026 (Pimasertib) Chemical Structure

CAS NO. 1236699-92-5

AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation.

Availability: In stock

Package	Price	Qty
5 mg	$40.00
10 mg	$70.00
50 mg	$180.00
100 mg	$300.00
10mM * 1mL in DMSO	$93.00
Custom Size	Get quote

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Biological Activity

AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation.

Solubility *

In vitro (25°C)	DMSO	78 mg/mL (180.89 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.19 mL	115.96 mL	231.91 mL
0.5 mM	4.64 mL	23.19 mL	46.38 mL
1 mM	2.32 mL	11.6 mL	23.19 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

*The above data is based on the productmolecular weight 431.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A10089
Actions	Inhibitor
CAS No.	1236699-92-5
Formula	C15H15FIN3O3
M. Wt	431.2
Purity	>98%
Synonyms	AS-703026, MSC1936369B
SMILES	C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.