Assay Controls & Cell Stimulation

Cat. No.

A15865

CAS No.

1219810-16-8

RSL3

Synonyms: 1S,3R-RSL3

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS.

Cat. No.

A16445

CAS No.

50-63-5

Chloroquine Phosphate

Chloroquine phosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator.

Cat. No.

A14616

CAS No.

16561-29-8

12-O-tetradecanoyl phorbol-13-acetate

Synonyms: TPA; Phorbol 12-myristate 13-acetate

12-O-tetradecanoyl phorbol-13-acetate is a diester of phorbol and is a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.

Cat. No.

A20681

CAS No.

28643-80-3

Nigericin sodium salt

Synonyms: Sodium Nigericin

Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator.

Cat. No.

A24102

CAS No.

28380-24-7

Nigericin

Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC.