Search by product name, CAS, target or catalog number. Press Down Arrow to reach product suggestions, Tab to move between links, and Escape to close suggestions.
Other Targets lists biosimilar antibodies whose targets fall outside the main groups or have few products. Examples include omalizumab and ligelizumab, which bind immunoglobulin E (IgE), and bimagrumab, which blocks activin type II receptors. Lirilumab targets killer-cell immunoglobulin-like receptors (KIRs) on natural killer cells. The group also includes antibodies to allergens, Wnt pathway receptors, proteases, transporters and intracellular proteins such as histones. Several fusion proteins and peptide conjugates are listed here as well, including the long-acting granulocyte colony-stimulating factor (G-CSF) analogs balugrastim and eflapegrastim.
ICT-01 is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting BTN1A1. This antibody is composed of an IgG1 type heavy chain and a human kappa (huκ) type light chain, with a predicted molecular weight of 146.2 kDa. For experimental controls, the recommended isotype control is Human IgG1 kappa.
CTX-2026 is a fully human monoclonal antibody that specifically targets CD277, a protein implicated in the immunological landscape of tumors. This antibody has demonstrated a potent anti-tumor effect in ovarian cancer models, suggesting its utility in oncological research focused on the modulation of tumor microenvironments. CTX-2026 is ideal for investigations into cancer biology, particularly for studies aiming to elucidate the role of CD277 in tumor immunology and therapeutic intervention.
The Anti-Fy3 Antibody (MIMA-29) is a chimeric mouse monoclonal antibody of the IgG2a, κ subtype, specifically designed to target the human Fy3 antigen. For optimal experimental control, it is recommended to use Mouse IgG2a kappa Isotype Control alongside this antibody to accurately assess antibody specificity and ensure accurate data interpretation.
The Anti-PACAP38 Antibody is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the peptide PACAP38. This antibody is comprised of a human IgG4SP heavy chain and a human kappa light chain, exhibiting a predicted molecular weight of 150 kDa. For isotype control purposes, the Human IgG4 kappa Isotype Control is recommended. This antibody is designed for the precise identification and study of PACAP38's role and function in biological systems.
Oloctinebart is a humanized IgG4-kappa monoclonal antibody targeting LGALS3. This antibody is specifically designed to inhibit the formation of amyloid beta oligomers, which are implicated in the pathogenesis of Alzheimer's disease and other amyloid-related disorders. Oloctinebart's targeted action makes it a valuable tool for research focused on the molecular mechanisms of amyloidosis and potential therapeutic interventions.
ALT-100 is a humanized IgG1 monoclonal antibody specifically designed to target NAMPT (Nicotinamide phosphoribosyltransferase). This antibody is engineered from the human IgG1 subclass and is suitable for various immunological applications where NAMPT is implicated, including cancer research and inflammatory diseases. For accurate experimental controls, it is recommended to use Human IgG1 kappa Isotype Control.
Synonyms: IXT-M200
Devextinetug (IXT-M200) is a chimeric monoclonal antibody of the IgG2κ subtype, derived from mouse sources, specifically targeting methamphetamine molecules. This antibody is engineered for high specificity and affinity in binding methamphetamine, making it an ideal tool for research studies focused on the detection and neutralization of this compound in various biological systems.
ATH3G10 is a fully human monoclonal antibody specifically designed to bind to oxidized phospholipids (OxPL). This antibody is engineered for high specificity and affinity, making it an ideal tool for research focused on oxidative stress, lipid oxidation, and related pathophysiological conditions. ATH3G10 is suitable for a variety of applications, including ELISA, Western blotting, and immunohistochemistry, facilitating detailed studies in cardiovascular diseases, inflammation, and other OxPL-associated disorders.
The Anti-TNFRSF21/DR6/CD358 Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets the TNFRSF21/DR6/CD358 antigen, a member of the tumor necrosis factor receptor superfamily involved in various cellular processes including apoptosis and inflammation. This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, and exhibits a molecular weight of approximately 150 kDa. For experimental control purposes, Human IgG1 kappa, Isotype Control is recommended.
CLN-619 is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target MICA (MHC class I polypeptide-related sequence A). This antibody is composed of a human immunoglobulin G1 (huIgG1) heavy chain and a human kappa (huκ) light chain, with an approximate molecular weight of 146.06 kDa. For isotype control experiments, Human IgG1 kappa, Isotype Control is recommended. This specificity and structure make CLN-619 ideal for detailed studies on MICA's role in immune response and its implications in various pathological conditions.
Synonyms: FP-1305
Bexmarilimab (FP-1305) is a humanized IgG4 monoclonal antibody that targets CLEVER-1 with a high affinity, demonstrated by an IC50 value of 4.51 nM. This antibody is effective in inducing a phenotypic switch from M2 to M1 in tumor-associated macrophages, a process critical for modulating the immune environment in oncological research. Bexmarilimab is primarily utilized in the study of cancer immunotherapy and tumor microenvironment dynamics.
OM-7D3-B3 is a high-affinity monoclonal antibody specifically targeting human claudin-1 (CLDN1) with a dissociation constant (Kd) of 4 nM. This antibody effectively inhibits the role of CLDN1 in facilitating the entry of hepatitis C virus (HCV) into host cells. OM-7D3-B3 is an invaluable tool for advancing research in HCV infection mechanisms and potential therapeutic interventions.
Synonyms: QGE 031; Anti-IGHE Recombinant Antibody
Ligelizumab (QGE 031) is a high-affinity humanized monoclonal antibody targeting immunoglobulin E (IgE). This antibody is specifically designed for the study of chronic spontaneous urticaria, providing a valuable tool for investigating the pathophysiology and therapeutic interventions of this condition.
The Anti-IL-4 Antibody (MP4-25D2) is a chimeric rat IgG1, κ isotype antibody designed to specifically target human Interleukin-4 (IL-4). This antibody is ideal for research focused on the modulation and signaling pathways of IL-4 in immunological responses. For accurate experimental control, it is recommended to use the Rat IgG1 kappa, Isotype Control.
Synonyms: MERS-D12; MERS Antibody-D12
Anti-MERS-D12 monoclonal antibody (mAb) is a human IgG1 isotype designed to specifically target the receptor-binding domain (RBD) of the MERS-CoV Spike protein, particularly the DPP4 interacting region. This antibody functions by effectively neutralizing the virus through direct inhibition of receptor binding, thereby preventing viral entry into host cells. Ideal for research focused on viral pathogenesis, therapeutic intervention, and vaccine development against Middle East Respiratory Syndrome Coronavirus (MERS-CoV).
Synonyms: KIND-016
Tirnovetmab (KIND-016) is a monoclonal antibody specifically designed for experimental research purposes. This antibody targets key pathways in disease models, offering valuable insights for scientific studies focused on its mechanism of action and potential therapeutic applications.
Synonyms: U 85855
Alvircept sudotox is a recombinant fusion protein that combines a segment of CD4 with a modified form of Pseudomonas aeruginosa exotoxin A. This biologic is specifically engineered for the study of HIV infections, exploiting the natural affinity of CD4 for the HIV envelope protein to selectively deliver the cytotoxic exotoxin to infected cells. Alvircept sudotox serves as a valuable tool in HIV research, offering potential insights into targeted cytotoxic therapies against HIV-infected cells.
Synonyms: Anti-Human IGHE Recombinant Antibody
Quilizumab is a humanized IgG1κ monoclonal antibody specifically designed to target immunoglobulin epsilon (IGHE, commonly referred to as IgE). This antibody binds to the M1-prime fragment of the membrane-expressed form of IGHE/IgE. The interaction promotes IGHE/IgE class switching and facilitates the depletion of memory B cells. Given its unique mechanism of action, Quilizumab holds significant potential for advancing research in asthma and other IgE-mediated conditions.
Atisnolerbart is a human IgG4 monoclonal antibody specifically designed to target BETVIA, the predominant allergen of birch pollen, known as Betv 1-A. This antibody binds with high specificity to Betv 1-A, potentially mitigating allergic responses. Atisnolerbart is suitable for use in various immunological assays to study birch pollen allergies and may be instrumental in the development of therapeutic approaches for allergen desensitization.
Rapaprutug is a monoclonal antibody specifically designed to target human KARS1 (lysyl-tRNA synthetase 1), a key enzyme involved in protein synthesis. This antibody effectively inhibits the inflammatory signaling pathways associated with KARS1, thereby diminishing the production and release of pro-inflammatory cytokines. Rapaprutug holds significant potential for advancing research into the mechanisms and treatment of inflammatory diseases.
LY2928057 is a recombinant human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting SLC40A1/Ferroportin. This antibody exhibits a predicted molecular weight of approximately 150 kDa. For experimental control purposes, the recommended isotype control is Human IgG4 kappa.
Synonyms: ASN-2
Berlimatoxumab (ASN-2) is a monoclonal antibody designed for experimental research purposes. This antibody targets specific antigens, providing a valuable tool for the investigation of cellular processes and potential therapeutic applications. Its precise specificity and high affinity make it ideal for use in various immunological assays and studies aimed at understanding antigen-antibody interactions within biological systems.
The Anti-TMEFF2 Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the TMEFF2 protein. This antibody consists of a human IgG1 heavy chain and a human kappa light chain, and has a predicted molecular weight of 150 kDa. For experimental control purposes, the recommended isotype control is Human IgG1 kappa.
