Other Targets

Cat. No.

AT1197

CAS No.

1356922-05-8

Bimagrumab

Synonyms: Anti-ACVR2B Reference Antibody; BYM338

Bimagrumab is a human monoclonal antibody designed to inhibit the activin type II receptor (ActRII), demonstrating high affinity with dissociation constants (KDs) of 1.7 pM for ActRIIB and 434 pM for ActRIIA. This specificity suggests its utility in investigating the mechanisms underlying pathological muscle loss and weakness. Bimagrumab serves as an essential tool for research focused on muscle degenerative diseases by targeting and modulating the signaling pathways involved in muscle growth and repair.

Cat. No.

AT1207

CAS No.

357613-77-5

Galiximab

Synonyms: IDEC 114; Anti-Human CD80 Recombinant Antibody

Galiximab (IDEC 114) is a primatized monoclonal antibody of the immunoglobulin G1 (IgG1) lambda class, specifically targeting the CD80 antigen to inhibit the CD80-CD28 interaction. This antibody features variable regions derived from cynomolgus monkeys and human constant regions. Galiximab is commonly utilized in the study of B-cell lymphoma, providing a valuable tool for investigating the role of CD80 in immune modulation and cancer biology.

Cat. No.

AT1210

Anti-TPSAB1 Antibody

The Anti-TPSAB1 Antibody is a recombinant human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets the TPSAB1 protein, which is critical in various biological processes. This antibody is composed of a human IgG4SP heavy chain and a human kappa light chain, with an approximate molecular weight of 150 kDa. For experimental control purposes, the Human IgG4 kappa, Isotype Control is recommended.

Cat. No.

AT1221

DCBY02

DCBY02 is a pioneering humanized IgG1 monoclonal antibody specifically developed to target CD93. This antibody is engineered to normalize tumor vasculature, thereby enhancing the infiltration of immune cells into the tumor microenvironment. Its mechanism promotes the efficacy of concurrent cancer immunotherapies, making it a valuable tool for advancing oncological research and therapeutic development.

Cat. No.

AT1222

Anti-DDR1/CD167a Antibody

The Anti-DDR1/CD167a Antibody is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target DDR1/CD167a, a receptor tyrosine kinase implicated in the regulation of cell growth and differentiation. This antibody is composed of a human IgG1 type heavy chain and a human kappa type light chain, with an approximate molecular weight of 150 kDa. For isotype control, the Human IgG1 kappa, Isotype Control is recommended. This product is ideal for use in research applications focusing on cellular signaling, cancer biology, and developmental processes.

Cat. No.

AT1228

Anti-Histone H3 Antibody

The Anti-Histone H3 Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting Histone H3. It is composed of a human IgG1 heavy chain and a human kappa light chain, and has a predicted molecular weight of 150 kDa. For isotype control, the Human IgG1 kappa, Isotype Control is recommended. This antibody is suitable for use in various biochemical assays where Histone H3 is a focus of study, providing essential insights into chromatin structure and function.

Cat. No.

AT1232

LIV-1205 (CBA-1205)

Synonyms: CBA-1205

LIV-1205 (CBA-1205) is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting Delta-like 1 homolog (DLK1). This antibody is composed of a human immunoglobulin G1 (huIgG1) heavy chain and a human kappa (huκ) light chain, and exhibits a molecular weight of approximately 150 kDa. For experimental control purposes, the appropriate isotype control is designated as Human IgG1 kappa, Isotype Control.

Cat. No.

AT1235

CAS No.

187139-68-0

Pegacaristim

Pegacaristim is a monoclonal antibody designed to exhibit thrombopoietic activity, effectively stimulating the production of platelets. This targeted biological mechanism positions Pegacaristim as a crucial tool in research focused on hematopoiesis and the therapeutic management of conditions associated with thrombocytopenia.

Cat. No.

AT1236

CAS No.

886584-10-7

Vanutide cridificar

Synonyms: ACC-001; PF 05236806

Vanutide cridificar (ACC-001) is a conjugate of the aminoterminal Aβ1-7 peptide. This biologic is specifically designed for use in Alzheimer's disease (AD) research, facilitating the study of amyloid-beta dynamics and pathology in neurodegenerative processes. Its application in experimental models provides a valuable tool for advancing our understanding of AD mechanisms and potential therapeutic targets.

Cat. No.

AT1238

CAS No.

2640981-30-0

Linavonkibart

Synonyms: SRK-181

Linavonkibart (SRK 181) is a fully human monoclonal antibody engineered to exhibit high affinity for latent TGFβ1, effectively inhibiting its activation. This selective binding is crucial for its role in modulating cellular processes associated with cancer, making it an essential tool for research in oncology and tumor biology.

Cat. No.

AT1240

Anti-MRC2/CD280 Antibody

Cat. No.

AT1244

CAS No.

2733621-19-5

Iluzanebart

Iluzanebart is a human monoclonal IgG1 antibody designed as an agonist for human Triggering Receptor Expressed on Myeloid cells 2 (hTREM2). This antibody enhances the survival and functionality of microglia by activating the TREM2 signaling pathway, thereby compensating for deficits in CSF1R (Colony Stimulating Factor 1 Receptor) function. It is specifically developed for use in research related to adult-onset leukoencephalopathy with CSF1R pathology (CSF1R-ALSP), providing a valuable tool for investigating the molecular mechanisms and potential therapeutic targets for this condition.

Cat. No.

AT1246

Anti-Meflin Antibody

Cat. No.

AT1255

Anti-KLK5/Kallikrein 5 Antibody

The Anti-KLK5/Kallikrein 5 Antibody is a recombinant human antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the KLK5/Kallikrein 5 protease. This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, with an approximate molecular weight of 150 kDa. For experimental control purposes, the Human IgG1 kappa, Isotype Control is recommended.

Cat. No.

AT1259

CAS No.

2923556-87-8

Nivisnebart

Nivisnebart is a human monoclonal antibody of the IgG1κ subtype that specifically targets SORT1. For experimental control purposes, it is recommended to use Human IgG1 kappa as an isotype control.

Cat. No.

AT1266

Anti-ACVR2B Antibody

The Anti-ACVR2B Antibody is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target the ACVR2B receptor. This antibody is comprised of a human IgG1 heavy chain and a human kappa light chain, and exhibits a predicted molecular weight of 144.42 kDa. For isotype control purposes, Human IgG1 kappa, Isotype Control is recommended. This antibody is suitable for a range of research applications focusing on the biological functions and pathophysiological roles of the ACVR2B receptor.

Cat. No.

AT1269

Anti-IGF-2 Antibody (DX-2647)

Synonyms: DX-2647

DX-2647 is a human monoclonal antibody that targets insulin-like growth factor-II (IGF-II), exhibiting potent anti-tumor and anti-proliferative properties. This antibody is specifically designed to bind to IGF-II, thereby inhibiting its interaction with the insulin-like growth factor 1 receptor (IGF-1R) and the insulin receptor (IR), which are critical pathways in cancer cell proliferation and survival. DX-2647 offers a promising therapeutic strategy for the treatment of cancers characterized by elevated levels of IGF-II.

Cat. No.

AT1273

CAS No.

1238217-55-4

Vatelizumab

Synonyms: GBR500

Vatelizumab (GBR500) is a monoclonal antibody specifically designed to target the α2 subunit (CD49b) of very late antigen-2 (VLA-2). This antibody is primarily utilized in the investigation of multiple sclerosis, offering a valuable tool for researchers studying the pathogenesis and potential treatments of this neurological disorder.

Cat. No.

AT1274

Anti-CD9 Antibody

The Anti-CD9 Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the CD9 antigen. This antibody comprises human IgG2 heavy chains and human lambda light chains, with an approximate molecular weight of 145.98 kDa. For isotype control, Human IgG1 kappa, Isotype Control is recommended. This product is ideal for research applications focusing on the role of CD9 in cellular processes and disease mechanisms.

Cat. No.

AT1277

CAS No.

167747-19-5

Sulesomab

Sulesomab (IMMU-MN3) is a murine monoclonal antibody fragment belonging to the IgG1 class, specifically designed to target Normal Cross-Reactive Antigen-90 (NCA-90) found on leukocytes. This antibody demonstrates enhanced localization to sites of infection, facilitated by its ability to exploit the increased permeability of capillary membranes associated with inflammatory responses. Sulesomab is utilized primarily in research focused on the identification and characterization of leukocyte dynamics during infection and inflammatory processes.

Cat. No.

AT1279

Anti-TCR Antibody (NKTT320)

Synonyms: NKTT320

Anti-TCR (NKTT320) is a novel humanized monoclonal antibody that specifically targets the invariant T cell receptor (TCR). This antibody is designed for use in cell-based cancer immunotherapy, offering a targeted approach to modulate the immune system's response against cancerous cells.

Cat. No.

AT1282

CAS No.

2669823-48-5

Nelmastobart

Nelmastobart is a human IgG4 κ monoclonal antibody targeting BTN1A1. For accurate experimental controls, it is recommended to use Human IgG4 (S228P) kappa as an isotype control.

Cat. No.

AT1284

Anti-PAR2 Antibody (PAR650097)

Synonyms: PAR650097

Anti-PAR2 is a monoclonal antibody specifically targeting Protease-Activated Receptor 2 (PAR2). This receptor is a key player in various biological processes, including inflammation and pain perception, making this antibody an essential tool for research in these areas. It is designed for use in a range of applications such as Western blotting, immunohistochemistry, and flow cytometry, providing researchers with a reliable means to study PAR2 expression and function in different biological contexts.

Cat. No.

AT1292

CAS No.

2769758-59-8

Cepeprubart

Cepeprubart is a human IgG2 κ monoclonal antibody specifically targeting SELPLG. For accurate experimental control, it is recommended to use Human IgG2 kappa as an isotype control.

Cat. No.

AT1294

Anti-YB-1 Antibody (21A3)

Anti-YB-1 Antibody (21A3) is a chimeric mouse IgG1 monoclonal antibody specifically designed to target human Y-box binding protein 1 (YB-1). For accurate experimental control, it is recommended to use Mouse IgG1 kappa Isotype Control alongside this antibody.