CBPD-409

Name: CBPD-409
Brand: Adooq Bioscience
SKU: A23966
Rating: 5 (288 reviews)

Catalog No.: A23966

PROTAC CBP/p300 Degrader

CBPD-409 is an orally active PROTAC degrader targeting CBP/p300, with a DC₅₀ of 0.2–0.4 nM. It shows potent antiproliferative activity in AR⁺ prostate cancer cell lines (VCaP, LNCaP, 22Rv1) with IC₅₀ values of 1.2–2.0 nM and demonstrates significant antitumor efficacy.

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CBPD-409 3037549-86-0 PROTAC CBP/p300 Degrader

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Grouped product items
Size	Price	Stock
1mg	$495.00	In stock
5mg	$1,380.00	In stock
10mg	$2,280.00	In stock
50mg	$7,590.00	In stock
Bulk Size	Bulk Discount

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Adooq Products cited in reputable paper

Biological Activity

Description	CBPD-409 is an orally active PROTAC degrader targeting CBP/p300, with a DC₅₀ of 0.2–0.4 nM. It shows potent antiproliferative activity in AR⁺ prostate cancer cell lines (VCaP, LNCaP, 22Rv1) with IC₅₀ values of 1.2–2.0 nM and demonstrates significant antitumor efficacy.

Product Information

Catalog Num	A23966
Formula	C46H52F2N10O5
Molecular Weight	862.97
CAS Number	3037549-86-0
SMILES	O=C(N1C2C(NC(CC2)=O)=O)C3=CC(N4CCN(C[C@@H]5CC[C@@H](N6C7=C(CN(C(C)=O)CC7)C(N8C9=C(CCC8)C=C(C(C(F)F)=C9)C%10=CN(C)N=C%10)=N6)CC5)CC4)=CC=C3C1=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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