JET-209

Name: JET-209
Brand: Adooq Bioscience
SKU: A23945
Rating: 5 (288 reviews)

Catalog No.: A23945

PROTAC CBP/p300 degrader

JET-209 is a potent PROTAC degrader targeting CBP and p300, with DC₅₀ values of 0.05 nM and 0.2 nM, respectively. It is composed of lenalidomide, a linker, and the bromodomain inhibitor GNE-207. JET-209 is a valuable tool for cancer research involving epigenetic regulation.

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JET-209 3033714-58-5 PROTAC CBP/p300 degrader

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Grouped product items
Size	Price	Stock
1mg	$486.00	In stock
5mg	$1,458.00	In stock
10mg	$2,484.00	In stock
50mg	$7,452.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	JET-209 is a potent PROTAC degrader targeting CBP and p300, with DC₅₀ values of 0.05 nM and 0.2 nM, respectively. It is composed of lenalidomide, a linker, and the bromodomain inhibitor GNE-207. JET-209 is a valuable tool for cancer research involving epigenetic regulation.

Product Information

Catalog Num	A23945
Formula	C46H47N9O6
Molecular Weight	821.92
CAS Number	3033714-58-5
SMILES	CC(N1CCC2=C(C(C3=CC=CC4=C3C=NC(C5=CN=C(C=C5)C(NC6CCN(CC6)C7=CC8=C(C(N(C8)C9CCC(NC9=O)=O)=O)C=C7)=O)=C4)=NN2C%10CCOCC%10)C1)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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