Nur77 | Adooq Bioscience

Cat. No.: A31000

CAS No.: 2469975-55-9

Nur77 modulator 1

Nur77 Modulator 1 is an effective modulator of Nur77, characterized by a binding affinity of KD = 3.58 μM. This compound up-regulates Nur77 expression and influences its sub-cellular localization, leading to Nur77-dependent endoplasmic reticulum (ER) stress and autophagy, ultimately promoting apoptotic processes in cells. Its notable anti-hepatoma activity makes it a valuable tool for research in cancer biology and cellular stress responses.

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1 mg

$45.00

5 mg

$115.00

All 7 sizes

Cat. No.: A37038

CAS No.: 2097787-75-0

Nur77 modulator 3

Nur77 modulator 3 is an effective modulator of Nur77, targeting the regulation of hepatic stellate cell (HSC) activation. This compound induces Nur77 expression, leading to decreased ECM deposition and enhanced autophagic flux that is dependent on Nur77. Additionally, it significantly inhibits the mTORC1 signaling pathway, resulting in reduced inflammation and amelioration of hepatic fibrosis in vivo. Nur77 modulator 3 is particularly useful for studies related to liver pathology and fibrosis research.

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5 mg

$35.00

10 mg

$60.00

All 5 sizes

Cat. No.: A85351

CAS No.: 2055829-03-1

Nur77 modulator 2

Nur77 modulator 2 is an effective Nur77 modulator with a binding affinity (Kd) of 0.35 μM. This compound demonstrates potent anti-inflammatory properties by influencing the colocalization of Nur77 at the mitochondria. It is a valuable tool for studying the role of Nur77 in inflammatory processes and mitochondrial function. Researchers can utilize this compound in various applications related to inflammation and cellular metabolism.

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All 3 sizes