Thyroid Hormone Receptor

Cat. No.

A23175

CAS No.

85541-78-2

(Glu2)-TRH

(Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS.

Cat. No.

A85430

CAS No.

3052978-35-2

THR-β modulator-3

THR-β modulator-3 is a selective THR-β modulator that demonstrates a significant reduction in total fat mass and body weight. Its primary biological activity indicates potential utility in the management of obesity-related conditions. This compound is useful in research focused on metabolic regulation, adipogenesis, and the broader implications of thyroid hormone signaling in metabolic disorders.

Cat. No.

A85486

CAS No.

2770373-00-5

THR-β modulator-1

THR-β modulator-1 is a potent modulator of the thyroid hormone receptor β (THR-β). This compound selectively influences THR-β activity, making it valuable for investigating disorders related to thyroid hormone signaling. It has applications in understanding the physiological and pathological roles of THR-β in various biological contexts.

Cat. No.

A85493

CAS No.

137348-10-8

Osteostatin (human)

Synonyms: Human PTHrP(107-139)

Osteostatin (human) is a bone formation modulator derived from the parathyroid hormone-related protein (PTHrP) 107-139 fragment. It has been shown to promote bone repair in animal models of bone defects and effectively prevent bone erosion associated with inflammatory arthritis. This compound is applicable in research focused on bone regeneration and the modulation of bone metabolism.

Cat. No.

A85507

CAS No.

2542029-56-9

THR-β modulator-2

THR-β modulator-2 is a selective modulator of the thyroid hormone receptor β (THR-β). This compound demonstrates biological activity by enhancing the metabolic effects associated with THR-β activation. Its applications in research include studying thyroid hormone signaling pathways and investigating metabolic disorders, making it a valuable tool in endocrine research and drug development.

Cat. No.

B21908

CAS No.

1073180-47-8

TR modulator-1

TR modulator-1 is a selective thyroid hormone receptor (TR) modulator. This compound exhibits significant biological activity in modulating TR signaling, making it valuable for studying disorders such as hyperthyroidism and thyrotoxicosis. TR modulator-1 aids in the exploration of therapeutic pathways and mechanisms involved in thyroid hormone regulation.