Imipramine-d4 hydrochloride is a deuterium-labeled form of the tricyclic antidepressant, Imipramine hydrochloride. This compound primarily acts as a Fascin1 inhibitor, exhibiting notable antitumor activity. Additionally, Imipramine-d4 hydrochloride inhibits the serotonin transporter with an IC50 of 32 nM and has been shown to stimulate autophagy in U-87MG glioma cells while inducing apoptosis in HL-60 cells. Its neuroprotective and immunomodulatory properties further enhance its relevance in various biological research applications.
Imipramine-d4 hydrochloride is a deuterium-labeled form of the tricyclic antidepressant, Imipramine hydrochloride. This compound primarily acts as a Fascin1 inhibitor, exhibiting notable antitumor activity. Additionally, Imipramine-d4 hydrochloride inhibits the serotonin transporter with an IC50 of 32 nM and has been shown to stimulate autophagy in U-87MG glioma cells while inducing apoptosis in HL-60 cells. Its neuroprotective and immunomodulatory properties further enhance its relevance in various biological research applications.
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