Other Inhibitors

Cat. No.

A13689

CAS No.

229971-81-7

Exherin (ADH-1)

Synonyms: NSC729477; ADH-1

Exherin is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.

Cat. No.

A11003

CAS No.

65-19-0

Yohimbine hydrochloride

Synonyms: Antagonil; Yohimbe; Aphrodine hydrochloride; Yohimbine monohydrochloride

Yohimbine hydrochloride (Antagonil) is a α2-adrenoceptor antagonist (pKi values are 8.52, 8.00 and 9.17 for human α2A, α2B and α2C receptors respectively)

Cat. No.

A12194

CAS No.

256925-03-8

AL082D06

Synonyms: D-06

AL082D06 is a nonsteroidal glucocorticoid receptor antagonist.

Cat. No.

A12288

CAS No.

105963-46-0

TOK-8801

TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator.

Cat. No.

A12355

CAS No.

81486-22-8

Nipradilol

Synonyms: Nipranol; Nipradolol; BRN 3566879

nipradilol is an alpha(1),beta-blocker with a nitric oxide donative action

Cat. No.

A12466

CAS No.

240427-90-1

20-HEDE

Synonyms: WIT 002

20-HEDE (WIT 002) is an antagonist of 20-hydroxyeicosatetraenoic acid (20-HETE).

Cat. No.

A12594

CAS No.

1796641-10-5

Parimifasor

Synonyms: LYC30937

Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity.

Cat. No.

A12643

CAS No.

125720-84-5

(E)-Alprenoxime

Synonyms: CDDD-1815

(E)-Alprenoxime is the isomer of the Alprenoxime. Alprenoxime is a site-activated ocular β-blocker.

Cat. No.

A12878

CAS No.

1104080-42-3

SNT-207858

SNT207858 is a 22 nM MC4 antagonist with a 170-fold selectivity vs. MC3 and a 40-fold selectivity versus MC5.

Cat. No.

A12913

CAS No.

1370554-01-0

Cilliobrevin D

Ciliobrevin D is the first specific small molecule antagonist of cytoplasmic dynein

Cat. No.

A13124

CAS No.

1064662-40-3

SNT-207707

SNT-207707 is an oral MC4-Receptor Antagonist

Cat. No.

A13178

CAS No.

187269-40-5

Bimosiamose

Synonyms: TBC 1269

Bimosiamose is a pan-selectin antagonist, inhibits E-, P-, and L-selectin with IC50s of 88 μM, 20 μM, and 86 μM, respectively, and can be used in the research of inflammatory disease.

Cat. No.

A13400

CAS No.

14556-46-8

Bupranolol

Synonyms: B 1312; BRN 2272923; Bupranololum; KL 255Ophtorenin

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity.

Cat. No.

A13919

CAS No.

22273-09-2

Fluorocurarine chloride

Fluorocurarine chloride is a short-acting selective sympathetic ganglioblocker with weak antagonist activity on the nicotinic receptor at the neuromuscular junction.

Cat. No.

A14052

CAS No.

2141977-22-0

YH249

YH249 is the first highly specific, direct p300/β-catenin antagonist.

Cat. No.

A15329

CAS No.

211364-78-2

R18

R18, antagonist of 14.3.3 proteins (KD ??? 80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation.

Cat. No.

A15334

CAS No.

481-42-5

Plumbagin

Plumbagin, exhibits cytotoxicity in rodent models of carcinogenesis and carcinoma; has antifungal, antiviral, and antibacterial action.

Cat. No.

A17177

CAS No.

2227996-00-9

EG01377 TFA

Synonyms: EG 01377

EG01377 TFA salt is a selective neuropilin-1 (NRP1) antagonist. CAS: 2227996-00-9 (Free base)

Cat. No.

A18880

CAS No.

2170608-82-7

PZ-2891

PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively.

Cat. No.

A19478

CAS No.

6266-66-6

PEO-IAA

Synonyms: 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid

PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).

Cat. No.

A19821

CAS No.

77422-99-2

PD 90780

PD 90780 is a non peptide antagonist of nerve growth factor (NGF) binding to the P75 NGF receptor, inhibits NGF-p75 NTR interaction with IC50s values of 23.1 µM and 1.8 µM in PC12 cells and PC12 nnr5 cells, respectively .

Cat. No.

A22147

CAS No.

433690-62-1

AA41612

AA41612 is an antagonist of melanopsin-mediated phototransduction.