Catalog No.
Product Name
Application
Product Information
Citations
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Drug Intermediate
Azidoethyl-oxime-Glucose-GalNAc serves as a versatile drug intermediate, primarily aimed at synthesizing disaccharide linkers. This compound plays a crucial role in the development of glycan site-directed antibody-drug conjugates (ADCs), facilitating targeted delivery in therapeutic applications. Its unique chemical structure allows for efficient modification and incorporation into complex carbohydrates, making it essential for advancing glycoscience research and drug development. -
Drug Intermediate
K-13 is a cyclic peptide compound that serves as a valuable drug intermediate through its role in organic synthesis. Its production involves a highly efficient synthetic route utilizing intermolecular and intramolecular Negishi cross-coupling reactions. This streamlined synthesis approach makes K-13 a significant reagent for research applications in drug development and peptide chemistry. -
Drug Intermediate
Methoxycarbonyl isocyanate serves as a versatile drug intermediate primarily utilized in organic synthesis. Its reactive isocyanate group allows for the formation of various carbamates and ureas, making it valuable in the development of pharmaceutical compounds. This reagent is essential for studying and optimizing synthetic pathways in drug discovery and development. -
Drug Intermediate
Guaietolin is an organic synthesis intermediate primarily used in the development of sulfonamide esters that exhibit carbonic anhydrase inhibitory activity. It serves as a significant marker of hypertension, as its levels are notably reduced in plasma metabolites of affected individuals. Guaietolin is applicable in research focused on glaucoma and hypertension, providing a valuable tool for investigating these cardiovascular and ocular conditions. -
Drug Intermediate
Bimatoprost isopropyl ester acts as a drug intermediate with a specific focus on the prostaglandin F2α analogs. It is characterized by a double bond at the 13-14 position and an inverted hydroxyl group at C-15. Notably, this compound has demonstrated significant biological activity, exhibiting an IC50 of 30 nM in FP receptor binding assays, indicating its potential role as an impurity in latanoprost formulations. Additionally, in vivo studies revealed that a dose of 3 μg can lead to a 1.9 mmHg decrease in intraocular pressure in normotensive cynomolgus monkeys, making it a valuable reagent for research involving ocular therapies. -
Drug Intermediate
Fmoc-Aeg-OtBu is a versatile intermediate used in solid-phase peptide synthesis. It acts as a building block for the introduction of pseudoproline motifs and backbone modifications, enhancing the stability and folding properties of peptides. This compound is essential for researchers developing peptide therapeutics and studying protein structure and function. -
Drug Intermediate
1-epi-Regadenoson ethyl ester is a key intermediate in the synthesis of the α-isomer impurity of Regadenoson, a highly selective agonist for the adenosine A2A receptor. This compound is essential for research involving adenosine receptor biology and contributes to the understanding of cardiovascular function and cellular signaling pathways. Its application extends to the development and analysis of therapeutic agents targeting adenosine receptors. -
Drug Intermediate
LBA-NHS is a derivative of lactobionic acid (LBA) designed as a drug intermediate. It functions by enabling the modification of lipids and acts as a coating for biological materials, enhancing the efficient and specific binding of LBA to carrier molecules. This compound is valuable in research applications involving drug delivery systems and biomaterials engineering. -
Drug Intermediate
5β-Dihydrocortisone acetate serves as a crucial intermediate in the synthesis of tetrahydrocortisone 3-glucuronide. This compound plays a significant role in biochemical research and pharmaceutical development, particularly in the study of corticosteroid metabolism and glucuronidation processes. Its use can facilitate investigations into the pharmacokinetics of glucocorticoids and their conjugates, contributing to a better understanding of steroid biochemistry. -
Drug Intermediate
1-Amino-3-(phosphonooxy)-2-propanone acts as a crucial drug intermediate in the synthesis of vitamin B6. This compound facilitates biochemical reactions essential for the production of vitamin B6 derivatives, contributing to studies in nutrition and metabolism. Its application in synthetic pathways enhances research related to vitamin synthesis and potential therapeutic developments. -
Drug Intermediate
AldoView precursor-1 is a crucial intermediate in the synthesis of the radioactive PET tracer [18F] AldoView. This compound serves as a selective tracer for imaging aldosterone synthase activity, making it valuable in the study of primary hyperaldosteronism. Its application facilitates non-invasive imaging and further research into aldosterone-related disorders. -
Drug Intermediate
Citreomontanin, an α-Pyrone polyketide, serves as a key drug intermediate in the synthesis of Citreoviripyrone A. Isolated from the mycelium of endophytic Penicillium species in Catharanthus roseus, Citreomontanin plays a critical role in facilitating research on compounds with biological activity. Notably, Citreoviripyrone A exhibits moderate inhibitory effects on the proliferation of HCT116 colorectal cancer cells, highlighting its potential utility in cancer research and drug development. -
Drug Intermediate
Fmoc-Aeg-OMe hydrochloride is a methyl ester derivative of Fmoc-protected aminoethylglycine, primarily used as a drug intermediate in chemical synthesis. This compound plays a crucial role in the synthesis of polyamide nucleic acids, facilitating research in nucleic acid chemistry and related fields. Its unique structure and properties make it valuable for developing novel therapeutic agents and exploring biomolecular interactions. -
Drug Intermediate
Valone is a critical intermediate in the synthesis of diorganotin(IV) complexes. Its unique chemical properties facilitate the creation of organotin compounds, which are essential in various applications, including agricultural and pharmaceutical research. This reagent serves as a fundamental building block for the development of advanced materials and bioactive substances in chemical research. -
Drug Intermediate
5-Bromo-1,2-difluoro-3-methoxybenzene serves as a crucial drug intermediate in synthetic chemistry. It functions as a precursor for the development of glucocorticoid receptor (GR) ligands, enabling the exploration of GR-targeted therapies. This compound is applicable in pharmaceutical research for the synthesis of novel therapeutic agents. -
Drug Intermediate
Geranylamine is an acyclic monoterpene amine that functions as a drug intermediate in the synthesis of various TRP channel modulators and antibacterial agents. Its structural properties make it a valuable precursor in medicinal chemistry, facilitating the development of compounds aimed at modulating ion channel activity and addressing bacterial resistance. This compound plays a crucial role in advancing research in pharmacology and therapeutic applications. -
Drug Intermediate
DFO-BCN is a chemical intermediate utilized in the synthesis of the PET/CT imaging agent DFO-CPC634 via click chemistry. This compound serves as a valuable tool in radiopharmaceutical development, enabling effective labeling and visualization in molecular imaging studies. Its role as a precursor enhances the efficiency of tracer synthesis, supporting research in diagnostic imaging applications. -
Drug Intermediate
((4-(tert-Butyl)phenyl)sulfonyl)methionine serves as a versatile drug intermediate in chemical synthesis. This compound is primarily utilized for the construction of peptides, facilitating the creation of diverse biological molecules. Its sulfonyl group enhances the stability and efficacy of peptide linkages, making it a valuable reagent in medicinal chemistry and drug development research. -
Drug Intermediate
2,4,6-Tribromo-3-methylphenol is a brominated phenolic compound widely utilized as a drug intermediate. It exhibits significant biological activity, serving as a precursor in the synthesis of various pharmaceuticals. Researchers employ this compound in studies related to organic synthesis and medicinal chemistry, facilitating the development of novel therapeutic agents. -
Drug Intermediate
(S)-Oxybutynin is a key pharmaceutical intermediate primarily involved in the synthesis of antifungal agents. This compound serves as an important building block in drug development, facilitating the creation of therapeutically relevant molecules. Its role in the synthesis pathway underscores its significance in both medicinal chemistry and pharmaceutical applications. -
Drug Intermediate
Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate primarily employed in the development of molecular glues. This compound serves as a crucial building block for the synthesis of GSPT1 degrader-9, facilitating targeted protein degradation research and applications in drug discovery. Its structural properties make it valuable in the design of innovative therapeutic agents. -
Drug Intermediate
Ethyl 4'-hydroxy-[1,1'-biphenyl]-4-carboxylate is a key intermediate for drug synthesis, primarily targeting biphenyl-based derivatives. This compound serves as a versatile building block in the development of various pharmaceuticals, facilitating the preparation of more complex molecules in medicinal chemistry. Its structural features make it valuable for applications in drug discovery and development. -
Drug Intermediate
4-Methyl-5-nitropyridin-2-amine is a key drug intermediate utilized in the synthesis of pyrazolo-pyridine compounds with notable cytotoxic activity. This compound plays a significant role in pharmaceutical research and development, enabling the exploration of novel therapeutic agents. Its reactivity and structural properties make it a valuable tool for researchers focusing on targeted cancer therapies and related biological studies. -
Drug Intermediate
SCP-1 (Compound C-1) serves as a crucial intermediate in the synthesis of the non-opioid analgesic drug SRP-3D (DA). This compound is primarily utilized in research focused on neurological disorders, particularly pain-related conditions. Its role in drug development highlights its importance for advancing therapeutic strategies in pain management and related pathologies. -
Drug Intermediate
Cbz-Val-(triAc-β-D-glucoside methyl ester)-Cbz is a chemical intermediate primarily involved in the synthesis of antibody-drug conjugate (ADC) linkers. Its structural components facilitate the conjugation process, enhancing the efficacy of targeted drug delivery systems. This compound is essential in the development of sophisticated biopharmaceuticals aimed at improving therapeutic outcomes in cancer treatment. -
Drug Intermediate
2-Hydroxy-2-(2-methylpropyl)butanedioic acid serves as a key drug intermediate in the synthesis of diverse pharmaceutical compounds. Its unique structure facilitates the assembly of various active moieties, making it essential for drug development research. This reagent is valuable for chemists working on the design and synthesis of novel therapeutic agents. -
Drug Intermediate
5-Deoxy-D-ribose serves as a crucial building block in the synthesis of various anticancer compounds. This compound is employed as a drug intermediate, facilitating the development of therapeutic agents targeting cancer. Its structural properties enable researchers to explore diverse pathways in drug development and biochemical studies. -
Drug Intermediate
Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl is a synthetic intermediate utilized in the development of molecular glue therapies. This compound plays a significant role in the synthesis of GSPT1 degrader-9, supporting research in targeted protein degradation. Its versatile applications make it an important reagent for studies focused on novel therapeutic strategies in cellular regulation and disease modulation. -
Drug Intermediate
Crotonamide is a chemical intermediate utilized in the synthesis of epidermal growth factor receptor (EGFR) inhibitors. Its application in drug development facilitates the creation of therapeutic agents targeting various forms of cancer characterized by aberrant EGFR signaling. Crotonamide serves as a vital precursor in the production of innovative pharmaceuticals designed to address critical oncological challenges. -
Drug Intermediate
Doxorubicin-Boc (Dox-Boc) is a drug intermediate utilized in the synthesis of the Adamantane-Doxorubicin prodrug. This compound plays a crucial role in drug development by modifying the pharmacokinetic properties of doxorubicin, potentially enhancing its efficacy and reducing side effects. It serves as a valuable tool for researchers exploring innovative cancer treatment strategies. -
Drug Intermediate
Elcatonin, a synthetic analog of eel calcitonin, functions as a drug intermediate with significant implications in bone metabolism. It is known to increase bone mineral density and inhibit bone resorption, making it valuable in research related to osteoporosis and bone health. Additionally, Elcatonin exhibits central analgesic effects, thereby supporting applications in pain management studies. -
Drug Intermediate
(R,1R)-Tenofovir amibufenamide is a crucial drug intermediate utilized in the synthesis of tenofovir prodrugs. As a nucleoside reverse transcriptase inhibitor, tenofovir plays a significant role in the treatment of HIV and hepatitis B virus infections. This compound facilitates the purification process, thereby enhancing the development and application of antiviral therapeutics. -
Drug Intermediate
1-epi-Regadenoson hydrazone serves as a crucial intermediate in the synthesis of the α-isomer impurity of Regadenoson, a selective adenosine A2A receptor agonist. Its role in the development of this compound is significant for research in cardiovascular pharmacology and adenosine receptor modulation. This reagent is essential for investigations into therapeutic applications targeting the A2A receptor pathway. -
Drug Intermediate
Fmoc-Aeg-OMe is a methyl ester derivative of Fmoc-protected aminoethylglycine, serving as a versatile drug intermediate in the synthesis of polyamide nucleic acids. Its structural characteristics enable effective incorporation into polypeptide chains, facilitating advanced research in medicinal chemistry and nucleic acid therapeutics. This compound is valuable for applications that require precise modifications in peptide design and functionality. -
Drug Intermediate
2-Methoxyphenyl benzoate functions as a drug intermediate, playing a crucial role in organic synthesis. This compound exhibits potential biological activity as a building block in the development of pharmaceuticals. It is widely applicable in medicinal chemistry and is valuable for researchers involved in the synthesis of complex organic molecules. -
Drug Intermediate
Nile Red phenoxyacetic acid is a versatile pharmaceutical intermediate primarily utilized in the synthesis of GPR84 fluorescent probes. This compound’s unique properties enable its application in various research settings, facilitating the study of GPR84-related biological processes and pathways. It serves as a valuable tool for researchers investigating GPR84's role in inflammation and immune responses. -
Drug Intermediate
Fluticasone propionate-C-S-CH3 is a versatile drug intermediate utilized in the synthesis of antibody-drug conjugates (ADCs). This compound serves as a critical building block in the development of targeted therapies, facilitating the effective delivery of cytotoxic agents to cancer cells. Its structural modifications enhance stability and drug efficacy, making it an essential component in pharmaceutical research and development. -
Drug Intermediate
Coumestan is a secondary metabolite predominantly found in leguminous plants, serving as a valuable drug intermediate. It is utilized in the synthesis of various coumarin derivatives, including Coumestrol, Glytabastan B, and Coumestan Pks13 inhibitor. Coumestan exhibits a range of biological activities, making it relevant in research related to anti-cancer, anti-inflammatory, antioxidant, antibacterial, neuroprotective, and organ protective studies. -
Drug Intermediate Control
Fluprostenol lactone diol is a chemical intermediate utilized in the synthesis of Fluprostenol, a synthetic prostaglandin analogue. This reagent plays a crucial role in pharmaceutical research, particularly in investigating ocular and reproductive health, as Fluprostenol is known for its potent effects on intraocular pressure and reproductive functions. Its development contributes to advancements in drug formulation and therapeutic applications. -
Drug Intermediate Control
(S)-N-Boc-L-homoserine ethyl ester serves as a synthetic intermediate in the production of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids. This compound is derived from L-homoserine and is utilized in various chemical research applications, particularly in the development of peptide-based therapeutics. Its role as an intermediate makes it essential for advancing studies in drug synthesis and nucleic acid chemistry. -
Drug Intermediate Control
Methyl (1S)-3-oxocyclopentaneacetate is a synthetic intermediate primarily used in pharmaceutical synthesis. This compound plays a crucial role in the development of bioactive molecules, facilitating the preparation of various drug candidates. Its unique structural features allow for diverse applications in the creation of new therapeutic agents within the pharmaceutical industry. -
Drug Intermediate
Montelukast impurity 15 is a chemical intermediate associated with the synthesis of Montelukast, a leukotriene receptor antagonist. This compound serves as a critical quality control standard for the assessment of purity during the production of Montelukast. It is utilized primarily in pharmaceutical research and development to ensure the integrity and efficacy of therapeutic formulations targeting respiratory conditions. -
Drug Intermediate
(R)-Benzyl mandelate is a synthetic intermediate primarily utilized in pharmaceutical synthesis. This compound serves as a versatile building block in the development of various drug molecules, contributing to the advancement of medicinal chemistry. Its unique structural properties facilitate the production of diverse therapeutic agents, making it an essential reagent in chemical research applications. -
Drug Intermediate
6-Piperazin-1-yl-isoquinoline hydrochloride is a synthetic compound that serves as an important intermediate in pharmaceutical synthesis. It is utilized in the development of various bioactive molecules and pharmacological agents. Its structural properties facilitate further modification and exploration in drug discovery applications, particularly in the study of neuroactive compounds. -
Drug Intermediate
2-Chloroethyl (2-chloroethyl)phosphonate is an organophosphorus compound primarily utilized as a drug intermediate in organic synthesis. Its structure facilitates the formation of phosphonate derivatives, making it a valuable reagent in the development of various bioactive molecules. This compound is essential for researchers engaged in synthetic chemistry and pharmaceutical research aimed at discovering new therapeutic agents. -
Drug Intermediate
(R)-(4-Bromophenyl)(phenyl)methanamine is a synthetic intermediate widely utilized in organic synthesis. Its unique structure allows for the development of various pharmaceutical compounds, contributing to research in medicinal chemistry. This reagent plays a crucial role in the modification of molecular architectures, facilitating investigations into their biological activities and therapeutic potentials. -
Drug Intermediate
3-Amino benzamidoxime, also known as 3-amino-N'-hydroxybenzene-1-carboximidamide, is a synthetic intermediate primarily utilized in pharmaceutical synthesis. Its chemical structure facilitates the formation of various active pharmaceutical ingredients, making it a valuable reagent in drug development. Researchers leverage this compound for its role in optimizing synthetic pathways and enhancing the yield of biologically active molecules. -
Drug Intermediate
2-Methyl benzamideoxime is a synthetic intermediate primarily utilized in pharmaceutical synthesis. It serves as a versatile building block in the development of diverse drug compounds, facilitating modifications that enhance biological activity. Its application in the preparation of complex molecules makes it a valuable reagent in chemical research and drug development. -
Drug Intermediate
GS-1427 intermediate-2 is a crucial chemical intermediate involved in the synthesis of GS-1427, a potent therapeutic agent. This compound serves as an essential building block in the development of novel pharmaceuticals, facilitating research into targeted therapies. Its role in the synthetic pathway underscores its importance in drug discovery and optimization processes. -
Drug Intermediate
tBu-MTX-CO-NH-C2-O-C2-N3 is an azide compound that serves as a valuable drug intermediate for the synthesis of chemical inducers of dimerization. This compound facilitates the development of targeted therapeutics by enabling precise control over protein interactions. Its chemical structure allows for the incorporation of ligands such as Aurora A and Cereblon, making it suitable for a range of biological research applications, including studies focused on cell signaling and protein regulation.
