PRMT5-IN-30 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with an IC50 of 0.33 μM and a Kd of 0.987 μM. This compound demonstrates broad selectivity against various other methyltransferases, making it a valuable tool in biochemical research. PRMT5-IN-30 effectively inhibits the methylation of SmD3 mediated by PRMT5, providing a means to study the functional roles of PRMT5 in cellular processes and disease pathways.
PRMT5-IN-30 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with an IC50 of 0.33 μM and a Kd of 0.987 μM. This compound demonstrates broad selectivity against various other methyltransferases, making it a valuable tool in biochemical research. PRMT5-IN-30 effectively inhibits the methylation of SmD3 mediated by PRMT5, providing a means to study the functional roles of PRMT5 in cellular processes and disease pathways.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
