Catalog No.: A14070

TACE/MMP inhibitor


TAPI-1 Chemical Structure

CAS NO. 171235-71-5

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $180.00

Special Price $144.00

2 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $660.00

Special Price $528.00

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Biological Activity

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
In vitro DMSO 97 mg/mL (194.15 mM)
Water Warmed: 59 mg/mL (118.09 mM)
Ethanol 97 mg/mL (194.15 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.03 mL 100.14 mL 200.28 mL
0.5 mM 4.01 mL 20.03 mL 40.06 mL
1 mM 2 mL 10.01 mL 20.03 mL
5 mM 0.4 mL 2 mL 4.01 mL

*The above data is based on the productmolecular weight 499.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14070
Actions Inhibitor
CAS No. 171235-71-5
Formula C26H37N5O5
M. Wt 499.3
Purity >98%
Synonyms TAPI1
SMILES C[[email protected]@H](C(=O)NCCN)NC(=O)[[email protected]](CC1=CC2=CC=CC=C2C=C1)NC(=O)C(CC(C)C)CC(=O)NO

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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