Tetramethylrhodamine-5-iodoacetamide

Catalog No.: A44322
Thiol-Selective Reactive Dye
Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that interacts primarily with cysteine residues in proteins, facilitating non-specific labeling. This compound is effectively utilized for covalently labeling proteins, which is crucial for tracking and studying protein interactions and dynamics. Additionally, 5-TMRIA can also be employed for covalent labeling of DNA fragments, expanding its application in various molecular biology and biochemical research studies.
Grouped product items
Size Price Stock Qty
5mg
$440.00
In stock
10mg
$670.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that interacts primarily with cysteine residues in proteins, facilitating non-specific labeling. This compound is effectively utilized for covalently labeling proteins, which is crucial for tracking and studying protein interactions and dynamics. Additionally, 5-TMRIA can also be employed for covalent labeling of DNA fragments, expanding its application in various molecular biology and biochemical research studies.
Product Information
Catalog NumA44322
FormulaC26H24IN3O4
Molecular Weight569.39
CAS Number114458-99-0
SMILESCN(C1=CC2=[O+]C3=C(C=CC(N(C)C)=C3)C(C4=CC=C(NC(CI)=O)C=C4C([O-])=O)=C2C=C1)C
Synonyms5-TMRIA
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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