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Biological Activity
VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.99 mL | 149.97 mL | 299.93 mL |
| 0.5 mM | 6 mL | 29.99 mL | 59.99 mL |
| 1 mM | 3 mL | 15 mL | 29.99 mL |
| 5 mM | 0.6 mL | 3 mL | 6 mL |
*The above data is based on the productmolecular weight 333.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18885 |
|---|---|
| Actions | Modulator |
| CAS No. | 1848252-81-2 |
| Formula | C16H19N3O3S |
| M. Wt | 333.41 |
| Purity | >98% |
| Synonyms | VU 0652835, VU-0652835 |
| SMILES | CC1=CC(O[[email protected]@H]2C[[email protected]@H](C)OC2)=CC(C(NC3=NC(C)=CS3)=O)=N1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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