ALK5-IN-10 is a selective inhibitor of the TGF-β type I receptor kinase ALK5, exhibiting IC50 values of 0.007 μM for ALK5 and 1.98 μM for p38α. This compound demonstrates significant potential in modulating the TGF-β signaling pathway, making it a valuable tool for cancer research and therapeutic development. Its specificity for ALK5 allows for targeted investigations into tumorigenesis and associated pathways.
ALK5-IN-10 is a selective inhibitor of the TGF-β type I receptor kinase ALK5, exhibiting IC50 values of 0.007 μM for ALK5 and 1.98 μM for p38α. This compound demonstrates significant potential in modulating the TGF-β signaling pathway, making it a valuable tool for cancer research and therapeutic development. Its specificity for ALK5 allows for targeted investigations into tumorigenesis and associated pathways.
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