Search by product name, CAS, target or catalog number. Press Down Arrow to reach product suggestions, Tab to move between links, and Escape to close suggestions.
Other Targets lists biosimilar antibodies whose targets fall outside the main groups or have few products. Examples include omalizumab and ligelizumab, which bind immunoglobulin E (IgE), and bimagrumab, which blocks activin type II receptors. Lirilumab targets killer-cell immunoglobulin-like receptors (KIRs) on natural killer cells. The group also includes antibodies to allergens, Wnt pathway receptors, proteases, transporters and intracellular proteins such as histones. Several fusion proteins and peptide conjugates are listed here as well, including the long-acting granulocyte colony-stimulating factor (G-CSF) analogs balugrastim and eflapegrastim.
Bremzalerbart is a human IgG4 monoclonal antibody that specifically targets BETVIA, identified as the primary allergen Bet v 1-A from birch pollen. This antibody is designed for the precise detection and neutralization of Bet v 1-A, making it highly relevant for research into allergic responses and potential therapeutic interventions for birch pollen allergies.
Synonyms: RG-7636
DEDN6526A (RG-7636) is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the endothelin B receptor (ETBR). This antibody is composed of a human IgG1 type heavy chain and a human kappa type light chain, with an approximate molecular weight of 145 kDa. For experimental control purposes, the recommended isotype control is Human IgG1 kappa, Isotype Control. This specificity and configuration make DEDN6526A (RG-7636) ideal for research focused on the physiological and pathological roles of ETBR in various biological systems.
The Anti-SERPINE1 Antibody is a human-derived monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting the SERPINE1 protein. This antibody is composed of a human IgG1 type heavy chain and a human kappa type light chain, exhibiting a predicted molecular weight of 150 kDa. For experimental control purposes, the Human IgG1 kappa, Isotype Control serves as the appropriate isotype control for this antibody. This product is essential for researchers focusing on the biological roles and regulatory mechanisms involving SERPINE1 in various pathological and physiological processes.
Synonyms: OMP-131R10
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody that targets R-spondin 3 (RSPO3). It is designed for use in scientific studies investigating advanced, relapsed, and refractory solid tumors. This antibody may serve as a valuable tool in oncology research, particularly in exploring the role of RSPO3 in tumor progression and therapy resistance.
Sapelizumab is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target IL-6Ra/CD126. This antibody comprises a human IgG2 heavy chain and a human kappa light chain, and exhibits a predicted molecular weight of approximately 145 kDa. For experimental controls, the appropriate isotype control is Human IgG2 kappa. Sapelizumab is utilized primarily in research focused on the modulation and study of immune response pathways influenced by IL-6Ra.
The Anti-EPOR Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target the Erythropoietin Receptor (EPOR). This antibody has a predicted molecular weight of 150 kDa. For isotype control, the Human IgG2 kappa, Isotype Control is recommended. This product is ideal for research applications focusing on the biological pathways and therapeutic targets involving erythropoietin and its receptor.
Mevonlerbart is an IgG4κ monoclonal antibody specifically designed to target Human Felcat allergen 1, a known allergenic protein. This antibody is optimized for high specificity and affinity, making it an ideal tool for research into allergic responses and potential therapeutic interventions related to Felcat allergen 1.
The Anti-RSPO1 Antibody is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target R-spondin 1 (RSPO1). This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, and exhibits a predicted molecular weight of 150 kDa. For experimental control purposes, Human IgG1 kappa, Isotype Control is recommended.
The Anti-CD8α Antibody (OKT-8) is a chimeric mouse IgG2a monoclonal antibody that specifically targets human CD8α. It is recommended to use Mouse IgG2a kappa as an isotype control for this antibody to ensure specificity and accurate interpretation of results in experimental setups.
Synonyms: 3F6-9G5
The Anti-AA2AR/Adenosine A2aR Antibody (3F6-9G5) is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets the Adenosine A2a Receptor (AA2AR), a critical component involved in various physiological processes including cardiovascular function and immune response. This antibody is composed of a human immunoglobulin G1 (huIgG1) heavy chain and a human kappa (huκ) light chain, and has a predicted molecular weight of 146.66 kDa. For experimental control purposes, Human IgG1 kappa, Isotype Control is recommended. This product is essential for researchers focusing on signal transduction pathways influenced by adenosine receptors and is suitable for a range of immunological applications.
Synonyms: TNX 901; Anti-Human IgE Fc Recombinant Antibody
Talizumab (TNX 901) is a humanized IgG1 monoclonal antibody designed to target and neutralize immunoglobulin E (IgE). This antibody is specifically engineered for the treatment and study of allergic reactions and other conditions mediated by excessive or inappropriate IgE responses.
Oberotatug is a human monoclonal antibody of the IgG1κ subclass that specifically targets the lymphocyte antigen LY75. This antibody is designed for high specificity and affinity in binding to LY75, a receptor involved in antigen processing and presentation. Oberotatug is utilized primarily in research focused on immune response modulation and the study of lymphocyte signaling pathways.
The Anti-Fc gamma R1 Antibody is derived from human sources and expressed in Chinese Hamster Ovary (CHO) cells. It specifically targets Fc gamma R1, incorporating a human IgG1 heavy chain and a human kappa light chain. This antibody has a predicted molecular weight of 150 kDa. For isotype control, reference is made to the Human IgG1 kappa, Isotype Control, which is recommended for appropriate experimental comparisons.
VIB-9600 is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically targeting FcγR2a/CD32a. This antibody is comprised of a human IgG1 type heavy chain and a human kappa type light chain, with an approximate molecular weight of 150 kDa. For experimental controls, the appropriate isotype control is Human IgG1 kappa.
Synonyms: BTT 1023; Anti-Human AOC3 Recombinant Antibody
Timolumab (BTT1023) is a recombinant, fully human monoclonal antibody designed to specifically target and bind to Vascular Adhesion Protein-1 (VAP-1). This interaction has significant potential for the modulation of immune responses in various chronic inflammatory conditions. Timolumab (BTT1023) is primarily utilized in research focused on elucidating the pathophysiological mechanisms and therapeutic interventions for chronic inflammatory diseases.
Synonyms: IMC 3C5; JNJ-69086420 antibody; Anti-KLK2 Antibody (h11B6
Alpitatug (IMC 3C5) is a recombinant human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target Kallikrein 2 (KLK2). This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, with an approximate molecular weight of 145.3 kDa. For experimental control purposes, Human IgG1 kappa, Isotype Control is recommended.
Synonyms: XT-M4
Anti-AGER/RAGE Antibody (XT-M4) is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells. It specifically targets the receptor for advanced glycation end-products (AGER), also known as RAGE. This antibody is composed of a human IgG1 heavy chain and a human kappa light chain, and has a predicted molecular weight of 150 kDa. For experimental control purposes, Human IgG1 kappa, Isotype Control is recommended.
Seniprutug is a human IgG1 κ monoclonal antibody targeting TRBV9. For control experiments, it is recommended to use Human IgG1 kappa as an isotype control.
The Anti-BACE1 Antibody is a human monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target BACE1 (beta-site APP-cleaving enzyme 1). This antibody has a predicted molecular weight of 145 kDa. For isotype control purposes, Human IgG1 kappa, Isotype Control is recommended. This product is essential for research focused on Alzheimer's disease and other neurological disorders, where BACE1 plays a critical role in amyloid-beta peptide production.
The Anti-CD24 Antibody (SWA11) is a human IgG1 monoclonal antibody specifically designed to target CD24, a cell surface protein involved in the regulation of cell proliferation and differentiation. This antibody has demonstrated potential anticancer effects, particularly in models of lung and ovarian cancer, making it a valuable tool for oncological research and therapeutic development. For accurate experimental control, it is recommended to use Human IgG1 kappa, Isotype Control.
ALT-100 (Human IgG4) is a humanized monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells, specifically designed to target NAMPT. This antibody is engineered with a hybrid heavy chain comprising both human IgG1 and IgG4 regions, paired with a human kappa light chain. It exhibits a molecular weight of approximately 150 kDa. ALT-100 is applicable in the study of inflammatory and fibrotic diseases, where Human IgG4 (S228P) kappa serves as the appropriate isotype control. For other research applications, Human IgG1 kappa is recommended as the isotype control. This product is essential for researchers focusing on the modulation of NAMPT activity and its implications in various disease states.
Alextatug is a human IgG1 λ7 monoclonal antibody targeting PABPC1. This antibody exhibits high specificity and affinity for the poly(A)-binding protein cytoplasmic 1 (PABPC1), a key regulator in mRNA stabilization and translation. Alextatug is designed for use in research applications to study mRNA processing and regulation mechanisms.
